ID W2K4N6_PHYPR Unreviewed; 2166 AA.
AC W2K4N6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=L917_19874 {ECO:0000313|EMBL:ETL79524.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL79524.1};
RN [1] {ECO:0000313|EMBL:ETL79524.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL79524.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TOG/XMAP215 family.
CC {ECO:0000256|ARBA:ARBA00025722}.
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DR EMBL; KI683018; ETL79524.1; -; Genomic_DNA.
DR EnsemblProtists; ETL79524; ETL79524; L917_19874.
DR VEuPathDB; FungiDB:PPTG_06010; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0043232; C:intracellular non-membrane-bounded organelle; IEA:UniProt.
DR GO; GO:0099080; C:supramolecular complex; IEA:UniProt.
DR GO; GO:0061863; F:microtubule plus end polymerase; IEA:InterPro.
DR GO; GO:0051010; F:microtubule plus-end binding; IEA:InterPro.
DR GO; GO:0030951; P:establishment or maintenance of microtubule cytoskeleton polarity; IEA:InterPro.
DR GO; GO:0046785; P:microtubule polymerization; IEA:InterPro.
DR GO; GO:0007051; P:spindle organization; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 5.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR024395; CLASP_N_dom.
DR InterPro; IPR034085; TOG.
DR InterPro; IPR045110; XMAP215.
DR InterPro; IPR048491; XMAP215_CLASP_TOG.
DR PANTHER; PTHR12609:SF0; CYTOSKELETON-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR12609; MICROTUBULE ASSOCIATED PROTEIN XMAP215; 1.
DR Pfam; PF12348; CLASP_N; 1.
DR Pfam; PF21041; XMAP215_CLASP_TOG; 2.
DR SMART; SM01349; TOG; 5.
DR SUPFAM; SSF48371; ARM repeat; 3.
PE 3: Inferred from homology;
FT DOMAIN 150..372
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 411..644
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 780..1021
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 1042..1282
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT DOMAIN 1390..1636
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REGION 35..96
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..406
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..770
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1284..1364
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1631..1651
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1700..1721
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2090..2111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2136..2166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 655..672
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..700
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 753..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1290..1308
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1321..1360
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2136..2156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2166 AA; 233391 MW; DE6109A5AFCDDE00 CRC64;
MAEKCLRNAS CKCSMCAGFD VASLMSISKS ISSNIKYGDD EEGDAAQEVA PPPPRFGGVV
NSPPAPSQKK SVVANSPPLR AVKRTPSAPA AVQNAHADTP MEDVSMAGAG AQDVVMESSP
TMKDTQMESV ASTLSNMEVD SPAAAGGQGE AVSIDAVLPK LTDKNWKVRK EGFEELKTLF
EQPGVKTNQV RPAMELFKKM CEDANASAME AGIAAVLAYT LNVEPFDKEI VSGVMARVTD
KGFSARPGIV KLCTELTDAF IAASAAEETV TALLEGTNNR KPKVPPACAT CILDALKEYG
PRVVPLQAIK TALPKLMEGA VKVRPIAMSI MVEIHRWTGP ALVQDIVANL RQAQQTEFEE
QTKDVVPGQA APTKFVRGAK PAKAAGGTAG KPSSGASGAA EPAAPAFDPR DFAETVDLLA
KLPKTEFKAK LALPKWSEKV EALKIVLELI GPVPKLANGD YYELVSTLKA LTNDSNVNIV
AKSIEVFGAL ADGLRKNFTQ YARMMFPELL RKLSDKKSVV LNATNKTLDL FLQHAMTIDM
MMDDLKLACD AAKNKAPPAR VQTMGYLSRA VENRYVDLND KALIVAFGGM FMKGIDDTDP
KVRDAGQKCF IVLLQATDQT AGWLQNMMDE ISRKNPRAFK TIQKGLGGGG GAASTPSSRP
GSAQSSRPGS APSRPGSAPP SRPGSAGSAA SRSSFGGSRT SEPDGDVEMD STPTPAGPRR
PSLKKRGPPS RLGMKPGAAG TSKAAPSRKP PAAGSSTGPS TGGGGSTDFT PIAISVTAEE
AEDIIAELQL DNWSSIQEGF ASSKWMERKG AIEGLEEYAR ANSSMMNVRV IEAFTMYLSK
QVKDFKDSNI NVLKSAFQAV GTFAETAASK FPRGVVCLVT PRACDKIGDR KANEAVRAMI
MQFCESTSPA YTTGCMIEYM PKVRLPLAHI EALVVLSECV KDFGISICNP RALIDFAKGP
QGLEGSNPKV RSAATSLLST MYSQLGPALL PILNLESWKP ALAKTVEDEF KKVGFDPAKA
QATVKRQVKD QDAAPAAADP GALFGRVDVS SQITKELLED MKNEKDKVAW KKRAEAMDSV
QAICEGAGCA IEFTRPVQEV LRSLKARLND SNANLKVKAA NVIGVVATSV GPDIAKMSKI
LGASLIAGVA DNKKTMQAAA IQALHKWVNH NNETSSACME SLLSPLSEGL LNTVGRAELL
GWAAEHLQKC EKLDLSSLVA PTVQCMMDKS SEAREKAQLV LAEVMKSVGK DVVFTTGCRD
IKPAAMRALK PLLQKVSDAV EASGGSTLGE VKASVPTSSA TPPVAPSATS GLERSGLKRR
ASASAGSTPV KSRLSRPGSL RAPTASSSSL SETSAKAGPL LKMTTNKPAR ISKGQYNKWI
FETTSTSEMN ARKGELEAEW KPYLSPEFHA KLFAPSLEKG MLAAMDELTL CIIHQADEVI
SSLDLVLKWC TLRIVDNNVQ ALAKLLEVLV KLFEMLKDTG YQLEDVEAAI LLPYLLQESG
QSKPRFRVRF RDVMKLVVDV YNPEKYVMYL MECFNGSKNM KSRCECIDLV EYIVGMHGYH
VVGRKCIKDV GKYVVAHEKE LRESAINTLV AVYMRTEGGN PDKFFRYAGI TTQQGTDLLN
ARLKHLPASS FQSEAPAPPQ QEAPERETAQ LQRPQRTGFG FGFARAAAAA TTAPTNNFAS
RPEEVQPVVE PVAIQQFNSE SYDEDVDMGA PENEATEEES QSAVIEELLL RPIEMLINSS
KEIVPAGTPA YKEGGNALKG LYAIINRPSD PAEVEFLHSY VNEIVLALCD CIHGAFYAGN
AEKRPEMYIL AISITTLTVV FNSDAVTSMQ RYTVERVLLE LCSKIMDPRM EKFAEKANLP
ASEIALLPPE EKRYLMVFKA LYKAMRKLTE RAKPGDVYPS VINLLQRLMH NDVGDYNKND
TLKHLLKEDS LDQLVGRILL KLSNVQANSL TPFEEIDIFG VLMQMHMFFS TLPGAEVMMV
DIANDNMRSA LKIMAESLMK TRSSAFEASM KDVPHTSPVR QALEEMGIGQ QQKDAIESTT
LRYGENGTTS NGTNTSLASA APPRITSHFG ANSAANGVAA APEESLTRRL FPPRDSGIAT
RTTRTTSAAP SLAETMLSAE SRGRSFTSFH AFSANRGAAT NTSRPSTTSA QLESLRERLQ
MSRHYN
//
