ID W2L7G3_PHYPR Unreviewed; 4627 AA.
AC W2L7G3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN ORFNames=L917_09141 {ECO:0000313|EMBL:ETL92580.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL92580.1};
RN [1] {ECO:0000313|EMBL:ETL92580.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL92580.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI679854; ETL92580.1; -; Genomic_DNA.
DR EnsemblProtists; ETL92580; ETL92580; L917_09141.
DR VEuPathDB; FungiDB:PPTG_11989; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
DR CDD; cd00030; C2; 1.
DR CDD; cd00102; IPT; 4.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 6.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR002909; IPT_dom.
DR InterPro; IPR031148; Plexin.
DR PANTHER; PTHR22625; PLEXIN; 1.
DR PANTHER; PTHR22625:SF69; PLEXIN A, ISOFORM A; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF01833; TIG; 2.
DR SMART; SM00239; C2; 1.
DR SMART; SM00429; IPT; 7.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR SUPFAM; SSF81296; E set domains; 5.
DR PROSITE; PS50004; C2; 1.
PE 4: Predicted;
FT DOMAIN 3382..3504
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 1526..1552
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2188..2211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2326..2385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3755..3785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4096..4136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4485..4593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1537..1552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2192..2210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2326..2367
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2368..2385
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3758..3782
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4105..4119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4517..4532
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 4568..4593
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4627 AA; 505671 MW; 461BFAF0CA25F1C8 CRC64;
MIRSSQRPIW ARRRGTRLLC MDRSYMAAQY YFNTMRLATS SAASRASATM QAPSAPALRL
RLIDPSVGVV SGGTRVVLHG AGFRPPPHSL TVRLRVDLQD AEYDNHSDTS DQLTWTSRPS
ISNTVDINGR FLLDTQLECV IPSFERQAAR VIAARMCLAA SSASVSSAPQ LVPLNVEVIL
NGGEQRSNTL SFKLHQPLEV RRICPQSVFM MSPAVTATVT LNILKLSIPA AHKLTPKGGQ
LEVLEGISTL PVFVRVKQTS ERTGAVSEQT REGKWKISPL GVYVVEFDAP TMGFGAVSVE
LSLNRVEFFK CKSDAPPEGF GYRVLRDVTL RAMEPACISV TSGQATEIKL VGDGFVDTGD
IVVAMVQKEL SSQVEKEVQV AQLNATYYGK NEVRCTVPAN LPFGCTSFSV SLNGGRQFGQ
SRVVGLLHRD RALEVVTPAS SSLAGGTAVT IRHSCLTLED VDAFHQLQRL DPPRRIRVRF
QPVSYSGSES GGLAKVVNAD ALSQTPGVLI CKTPNFMENI KALNGMRAAG ASENDGDSVP
YIWRFTVAIA LGGDFFQGDL PFSFYLPPVI RSLTQHHGPS TGDTCVKLRM KHKVPPRLKL
LIRFSTLDFT KSMTTEGHVV EPNTTTIQDS KIESIAPQQI DDDPEYLISC TTPPWTENLA
GTTREVPHVT ILQVSYDAGV TFYPVIDPPP TVTQSNPLAK DLSYLCFLFY PPPIVRSATP
LSADILGGSH VRLQGEHLVD HGAQMSVIFE SSTMSRKVSA FVEKGELRCC APPFNVGRAR
VFVSLNDEQY TLCDLHDPET NAPVEFIFYS SPTVTRISPL CACVRQSSEL KIYGTNLIET
DRIKVRVSFP ASAGRRLVFK DVPGTAHNGV ITATTPVFPD EYANQNALVD VALNGANLSG
TSVPLRYFSK YGITRVDPPL GAFEVPVTLT VFLAPVIVTD KILVRLRLGF IKTTAEHEPS
KQELEIMYGP VEASTWTASS VEVLIPALSS LVESLPVLTT VHVEVSFDDV HFHGVGDLRD
HYRVYNIPQL TSATPLFGLS DRETRIMAHG VHMRPDGVVK LTLFLESTSA DKKSKDRRVA
TRAALVPVTT VTADVNVKRQ RLSFTCPSLS QLRASTDRQS APFIAPSPGI INGVPDRRIQ
GDSVGGMLLP ERVIMQISVI DGQPISLPFV FRYYRAPTLV SMNPRVGYVC SGSIISFEFA
ERIATPTVDF RFGDSLPTSG RIRDERFVEC FSPELSAGTH SISISFNEQH YELAVLMEHK
VESQEDNQLS VATFHAFPLP VFVLPPAGRD RVYAFGPTSG GTVVVIKGKG FVPDTKIYVR
FASQFKDAFD GQSEIIVGAK VVDGETIRCI SPPSMRLGRA VLHVSYNLQQ FSDSTCYFEY
HAPTRYVAKG TLCGPISGQT PLKLVVEDMK GLPSHTQLLQ CAVRFESEKS HASVDVDAQF
DQETCVLSCI TPAWPSNELV SLRVSLSRGE GELFEDTRIK FLFYDPPEGV IKIEPAAGPI
GGGTEVLAWC GSIVETGEIT VSIQLSKPEP DRPNLTKRRS STTLTPPLSR KSSLRGKQIF
PPILVRGEIV GESVRFTAPP VEGPCTAVLG ISLNGINYTS AQRPLHFTYY VGPVLRRINP
GWAALEGTNE ALVIEGEHIR DFSCKLLVRF SLQDEKQPEQ NGIVVGAQFI STSATSDGAL
RCVFPAAPPG FYELEISLNG QQFSQSQYVS KTFGNLSGTA CTALLPFRHF SSPFCLATAT
GPAAGGSTVV LFLGGKLLKI LSRETKCQVQ FKPIRGTEKI THVPLSNTNG GTGLIKPSSN
VADVMCVAGD IDHVNARVTC RAPLLRVACV SNVDILLPSG SGASTACQLF GLRSSEREKY
YSYESPSITE IAPSCGPVSG GTQLVIEGAN ILDTAQIFVR FRSSSNEREF VLVPARYSRT
FPGGSASVSP LIICNTPPVE FVDKTISTGI ETAAQSTSLL TQPSPRNREG VAAGKARTQT
YQMLAEQSLK VHRASVAQGN NDAGLGILRI TRPSVKATPR GNCEAESGAT VLVDFTLNAG
EQFITHSVRF HYYQDIDPRQ VKWTPRHLPT QSLGGRQATD SRLLTVALPK AFRLTESPER
VCFRFDGVDA NLQLSMRRKS SVLLHETESL TELVIANPPK FQTQSTMRRS ITYFQNSILS
SENLPVSPPV SPRNDSIGAA APIRRQAIGT HGMTSRPITP DVSSPRPATT GPSPCIAGKV
ISANEVTCIV PDFPTPGTVQ VFFSPNAQQF VCLGELLFHP AMVIKDEYHH TTFRFCSNVG
GSPFALQCSP STVLRYLAPE DVTTADKRHA QIQDLGLRKN SVALEEARSR NSQASREIKD
EATSIRDNDQ KEEDSDPDAR TIDEIDENKA DELENEDEDD DACDVTPEPV ERWQKRSFHA
AQVFLIPANV KLLKRVTMTA TRVDNRCEAG KSVPDDAGCC IFDMSNWGEQ VLLRAVLPSS
CGYTSYSSVI EPSVFHEEQK SSTTHLVLTQ LPAAGKVHVA VIGPFEVQLN AVIIDGSGKD
ITTATTHFEA EEQDNVRCSL TSVDPTVLVD SACDVCYVCV RFGAIDNETF SASGQDITNV
QVLVSDSSGV QLCLCGPPVK SSMWIVGRLS LQPFDPASPS RTIEAVDKLV QDVPEDSTVY
SELKNLLMSL ALASKRSNTV SSQSYTVPVM FEFTSGDSSR NITASSRARL VLSASDNFQT
LLAISLSPQT TNGPTVTLEC AMPSLSFSGI ATLVVSCGGV VFSNSVTVHC YDPRSWKVIA
LSPPCGQLPL CQDPKEPLEP MTLRLKGEHF VENRKIMVRV SDKDRYFTTP GKVDQVHVLS
LRIAAVKNLR VLLQPLGIVP HASNAGPSGA TQKKEEKYLS SVVSGTAGGS IVALVSTWST
FTFTVRIECG DQRLFASCRE NSVFAAISTG SVLSWEEEFE LRIAADRRAP LLLTAELSES
SLPKPLELAQ AWVPLNGIQV GSSDIRRYTA RFEEHFKRGY YVGSESTAGA ATEVELLLQL
SPLMLHPDYI VSQIPYALLR QLSPQPLDVQ VSSGDGFYST PHSFVVYKPP TVTLTTPSVL
PRSAGGDVIV TGTGFVNSGR VCVRLFAFKK NRFNNNSEEQ RALATINRVQ RFQRTESTND
GFFPYFSRDV EGVFVSTSSL KFRMPSYMTS YNVYYSVSFD GRSFTEASHV SNVLLFSINA
VSPKGGPISG NTYATLHGTN IDACLSSRSG LTPLVRVTWK RGARDLEHVT VPGEFYPHED
AVYFYSPQSK FGLYSVAVNV ELALISSGTG ADTVPRFGRD EVSFVMYKTP TIKSVAPLTA
LVSGVSTTEI IVQGFEEKAV SNMRLAPKLR FKRRGQMQVS DAQLVSESRF DCIVPRFNVP
NAVATELPLS GIPPVHRVRA GGALSPRRNT SQPKLWTRTA GVFVALLGAR NLRASKKNAC
NPFAVVYVGK LQLKSTRKDG VFSPVWNELF DFEWPSDSDS NLASVRVVFE NQLTADQSES
LGHVELKFPV KDKLTQAFAL RAWLPLRRIR GKYYRKENEE TAVKNLKTSK QAPAPSISTS
NLGEVELAIA FVPPVTQAKK HKKALRSSII SVITTQPQSR KPSQAKGGLS TYSLKKEKLL
RAFRQRGAPV SLVPTELAVE LALNGQDFWS VAPSTCYSIL TPIVVDVEPK FISIAGGSTL
YVSGNNFVNT GCLRVAFAVV TKDDTTQTLG SERTIVVEAK YRSSTSIVCM TPPLKLATEA
SYVNVYVSLN GSDFDGIALP KQLIKLSEPA AERPLTGVNV DERIEESDET EEPPRKSPRK
NTENDSAITL VSEQYVVDCK RIISLALDGN GSGGFLSTRL ATSRNENFLL VPQVRVYLTP
KVTRVRPTDG IYTSHLTIDG TNFTNTGIAT ARFSSQFADA EVRTAKLVVV SSTRMECCVP
DFPRGVMVRI SVAMNGVEYV QCPGELRVFQ SPRLTELYPN WVSANTTVEL ELRGINLTAA
IASMDNNRDQ EDTASIQVSF SNTREKEVVR GKYEDGKVRC SIPREIWRAS SRDKRSHSPT
AKTSPILVDI WLGGKFTGSP LPLHVYRDIP TVHLVSPMDG PVYGGFAIVV EGRGFIDTGK
IVVRFQLYSD QRESTPRIED ESSRVSQSQR VSPTKSVNTL EKRQGKEGAA NGKTNVEASS
ESASFVDVAA KFVSAERVLC PAPAFPQEGV YTVLVALNCV EFSRVSDGSW FLAWQNWQKR
KRLLSHALFS RASAANDAAS AAAIAGAAAA SASLDEDDIE KLKRKSSFML PKIRSALAAT
PEDSSTFRAK NNELVSDNSL ASDDTEEMLM KDPKLLQWCP TSWMETRVSG RPLLSLLEYL
CGIRETQQFI CRRLRVAFRL KSSQSRGGDS TEVPALRFNL FVEAIRMIFL NALMRELEEL
WHAAEHRPDG TMTIKQLLRR LLRNAASDQR SMSPEPGPTH YDPRYSIVSS RETAAIILPP
VAQPKNISDP PSTLFMNYDA AVQAVKPRAP RPVFRKRKFN TSWCNPVVEG AKEPTPSPRP
PSQVNKTRPS PRTRVSEDMV TEVSTTLTAI GGATGTDEDK AAESQAGNQV DVHQQEATAK
EDAVRTPDQV TIASSKPARS LPPSTPATNT MMPRQATLSG PNPFYNDIAP LYAKFLNSTE
VKRFLKQ
//
