ID   W2LAY9_PHYPR            Unreviewed;       694 AA.
AC   W2LAY9;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   RecName: Full=RING-type domain-containing protein {ECO:0000259|PROSITE:PS50089};
GN   ORFNames=L917_08030 {ECO:0000313|EMBL:ETL93934.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL93934.1};
RN   [1] {ECO:0000313|EMBL:ETL93934.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL93934.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   EMBL; KI679498; ETL93934.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2LAY9; -.
DR   EnsemblProtists; ETL93934; ETL93934; L917_08030.
DR   VEuPathDB; FungiDB:PPTG_11751; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   Gene3D; 3.40.50.10190; BRCT domain; 1.
DR   Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR   InterPro; IPR031099; BRCA1-associated.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   InterPro; IPR017907; Znf_RING_CS.
DR   PANTHER; PTHR13763:SF0; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN; 1.
DR   PANTHER; PTHR13763; BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN BRCA1; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF13923; zf-C3HC4_2; 1.
DR   SMART; SM00184; RING; 1.
DR   SUPFAM; SSF52113; BRCT domain; 1.
DR   SUPFAM; SSF57850; RING/U-box; 1.
DR   PROSITE; PS00518; ZF_RING_1; 1.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00175}.
FT   DOMAIN          48..86
FT                   /note="RING-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50089"
FT   REGION          153..191
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          342..430
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          507..534
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          614..638
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        175..191
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..368
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        401..422
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   694 AA;  77219 MW;  4A15B918DECA6350 CRC64;
     MLRISSATFV RLARLSDHFA QLLLAEMAPW TLQRLERAVE NFSDQLQCAI CLCAYDNPVS
     LPCNHCFCEE CIHRALELKA QCPICKTPAK KRRLRYDTTV QELLRATEML CAAPDPNAAA
     AARKTPPKTE KRVKKELTQV KVATPVTKVA AGKTTKVAAK TATPEKKMTP RRGTKRNSQK
     SPPSTPTLMD KWVTGGSVQL KNGFKIKKEK PSTSVLTPVR RRAQTQEINS QVAVTQMSPP
     LFEISSGGNA ETTDAVDENK LMPWRRRPNA DVLVLDNDAT DTAMDETQLD AAECNSLAIS
     PRRRRNTTDV VTVDTAFSPW RRRRRWRQSD ENNDAVDAVV AETQLETVEM EQQETPTRRR
     RSDSNGVAMD ETVDETQLEA VEPKYQKPTP RKRRRSPANG VATDDNANGT VDTKQQPVPN
     GKIPVRNGSA ESPSLIVDSQ AQPLPEVEVF QVGDLVDVIE RQWVGINKRG GAGRITKVHG
     DGFYAVKFVI GSGSDSRVPG TFIRRPTEDL VSDSTPSRAV RKRQRRRPSD TMVSPDLLTI
     KTKSSPHSTT KKTKTKSIAI GKHSGMVFLC SGFKEDRMQQ IDEWAELLGA EVVHYWSNDV
     THLIVKCVSG DEIEKEGPSM DDSNSESSPQ APKHGKRQLF GDRKSGRWVK IRSLKYLKAL
     VGGRWIVSDE WLQGEDMLSS IAAYLMLTVA LIPC
//