ID W2LFZ8_PHYPR Unreviewed; 1157 AA.
AC W2LFZ8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=BUB protein kinase {ECO:0000313|EMBL:ETL96372.1};
GN ORFNames=L917_06112 {ECO:0000313|EMBL:ETL96372.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETL96372.1};
RN [1] {ECO:0000313|EMBL:ETL96372.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETL96372.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI678920; ETL96372.1; -; Genomic_DNA.
DR AlphaFoldDB; W2LFZ8; -.
DR EnsemblProtists; ETL96372; ETL96372; L917_06112.
DR VEuPathDB; FungiDB:PPTG_02534; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0000776; C:kinetochore; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0007094; P:mitotic spindle assembly checkpoint signaling; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.430; -; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR015661; Bub1/Mad3.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR013212; Mad3/Bub1_I.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR14030:SF4; BUB1 KINASE, ISOFORM A-RELATED; 1.
DR PANTHER; PTHR14030; MITOTIC CHECKPOINT SERINE/THREONINE-PROTEIN KINASE BUB1; 1.
DR Pfam; PF08311; Mad3_BUB1_I; 1.
DR Pfam; PF00069; Pkinase; 1.
DR SMART; SM00777; Mad3_BUB1_I; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51489; BUB1_N; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ETL96372.1};
KW Transferase {ECO:0000313|EMBL:ETL96372.1}.
FT DOMAIN 127..284
FT /note="BUB1 N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51489"
FT DOMAIN 840..1152
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 44..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 519..570
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..390
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 519..539
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..570
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1157 AA; 132142 MW; 39C977D9BDFDF621 CRC64;
MNTALVVTRA RLQYVTVVRY LLSNLAGFQN FELEREVRTR SAHTIQNPSV VRDERDRQRS
SQKPTPMTMD AALSDRKRKA DAFEWEASKE NVMPLKRGRN VADLNKALRA HDSFQTKLRL
EDELKAKQDA VEAYNGDDPL AAWLEYIRWL EVKMPEDTRK KFTALEKCTR ELKDNPHYKN
DMRYIRLWIQ YADLVSNPKD IFKYLYQNKI GERVSLFYIG WAYVLETMAN YPQAHKIYLK
AGQKNAEPQD LLERKYKEFQ RRMSRQWLRM TEETGANGID ERQQLHQHRA SARVQRIQKA
NAHKPVFVVY EDPVGHSVDP FDGNGGWKKL GTMQQQDKEN EMAPSAWNTL AARGESGAGA
GRQSDRRSPP GRNSRPQDAS TLQVFVDEEF SVSESEQKRR TPLTHRSQTL RQRLDGVATE
EEMLAQEPLK NFTASDKKAR AQKQVTKGRS EKSCYDVEQI TSSTGDAISF EEIRASAYQQ
AVDRHRELEH RALHDVTHEV DSASNVTLSL SAATSSVTAS VASHRANPSA PTTTSSTSRE
VESPERKPAP LATAAQTAAV STHNGEQEDM TINTRVALED INSMFCSPPR QPKPSVWDAK
EGDPVERKLH FSVFEDSVDS VALNAQDQSQ RQDINESIPK QTFQVFKDDA SAEPLVGRKQ
DFQIFSDGAP EEPRTGKAFQ VFSDDVPEEP RTGKTSWSQK RKPLGARDDL VCSVRLTNKD
VLMRVQKDAA EKDSTESRWI QGTTKNLARE GSSRNITQPT PKSVTHLSTK VPVAALVLDP
YTFENRQNLI LDRRVDWYLC SRPDAVKLHS QTLPRVPCTN PVKRKLPKPI VFKASTTLTV
QLVGVLGSGS FAYVFSAKVV DTTINSTRNK AVKIEKERQN LAWEFYITNK IKKKLRIERG
IPDEKIPVPT LTELHLFSNG ALLIMDKGHV GTLFDVLNCY KQWGTTFPEV LAVYYGIKML
RCIELLHSAN VLHGDIKPDN WLMIPGNPSS ELELISQEPK LDKVYQAGDL YLIDYGRSID
LSFYPDGTVF RGSCHAKGFQ CVEMLTQRPW TYQIDTFAFC GTMHCMLFGE YMEVKPKRNA
KGATHWGIVR QFKRYWQVDM WENFFHVLLN VHSCTDQPSL LNLRRRMERY FVSDRSRQQE
LFKQLSRQDS VLRKTTV
//
