ID   W2LVP3_PHYPR            Unreviewed;      1097 AA.
AC   W2LVP3;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   RecName: Full=NFACT RNA-binding domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=L917_01885 {ECO:0000313|EMBL:ETM01543.1};
OS   Phytophthora parasitica (Potato buckeye rot agent).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM01543.1};
RN   [1] {ECO:0000313|EMBL:ETM01543.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CHvinca01 {ECO:0000313|EMBL:ETM01543.1};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the NEMF family.
CC       {ECO:0000256|ARBA:ARBA00008318}.
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DR   EMBL; KI677687; ETM01543.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2LVP3; -.
DR   EnsemblProtists; ETM01543; ETM01543; L917_01885.
DR   VEuPathDB; FungiDB:PPTG_19141; -.
DR   Proteomes; UP000054423; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0072344; P:rescue of stalled ribosome; IEA:UniProt.
DR   Gene3D; 2.30.310.10; ibrinogen binding protein from staphylococcus aureus domain; 1.
DR   InterPro; IPR021846; NFACT-C.
DR   InterPro; IPR008532; NFACT_RNA-bd.
DR   PANTHER; PTHR15239; NUCLEAR EXPORT MEDIATOR FACTOR NEMF; 1.
DR   PANTHER; PTHR15239:SF6; RIBOSOME QUALITY CONTROL COMPLEX SUBUNIT NEMF; 1.
DR   Pfam; PF11923; NFACT-C; 1.
DR   Pfam; PF05670; NFACT-R_1; 1.
DR   Pfam; PF05833; NFACT_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490}.
FT   DOMAIN          579..698
FT                   /note="NFACT RNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF05670"
FT   DOMAIN          949..1068
FT                   /note="NFACT protein C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF11923"
FT   REGION          286..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          728..957
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1008..1040
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1068..1097
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        759..773
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        795..851
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        868..889
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        901..915
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        929..945
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1009..1034
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1097 AA;  122731 MW;  6B175D644C4E5CDC CRC64;
     MKKTRMSIDD IHAMVGSIRA NVVNMRVTNI YDVQGQGDGG AAKTYILKLH QPPFPKVFLL
     LESGVRFHTS KYARDAKAGN ALPSQFTMKL RKHLRGKRLS ALTQLEGDRV VDFTFGQGAL
     KCHLILELYA SGNIILTDGD YRILSLLRTH RFDENVKMAV KQEYPVQLLG DQEKQRGIQT
     TEQLTEFVNR WFEEQEAKAA IAVPGKTQKK KKAQTIKQLL LVKESTFGGL GPVIIEHCLV
     RADISPTLKI KNAAEFTALG EDKLAALLAA IQEGWKLLER LRDEQTSVNG PVPVQNDDTA
     EAGDSDEEDA APTTTKTSST TSQKCGFIIL KDSADENAPE QFEEFTPFLY AQHLQAHKKV
     KSFDTFDEAV DEYFSRFEAE TAEVAKQSAQ IAAENKLAKL KKNQQQQLAQ LREVQEQSFQ
     HAQLIEANQQ DVENVLLVIR SALASGMDWR GLEELVRYEQ KNGNPVASLI HQLDLEHNRV
     AILLCDDDDD DEDGDGGDGT GEEDKKAHVI WIDLSLSALA NAREIYTKKK KAGEKVKKAT
     EATDKAIALA EKNTKKTLEK QQTKRNVIYQ RRKTHWFEKF HWFLSNEKYL VVAGKDAHQN
     ELLVKRYLRK GDVYVHADLH GAATCIVRNH ATVKDKKTQE LPPIPVATLE QAGCMSVCRS
     NAWTSQVIAG AYWVHADQVS KTAPAGEYLT TGSFMIRGKK NYIQPSRLEM GLAILFRIDE
     SCISNHARQG EGRVSRIDEG PEDDEGEESA SPVAEVQPEK QTTEEESVPD ESMSKPSKEV
     TVVQENESDA HEEEDEVSAQ QTQREGRKRL SAKERRDMKK GKAPAREESI DEQPPVQQKR
     GKGKDKTPTQ APQKKSVRGK KGKMKKMKKK YADQDEEDRR LRMEALGHVV EDEQEDDEPT
     KENDSTEHSG DEDGDNTTDG NTTTEVSEEY IRQQREKKEK YLDEQEDEAE GADFFDAFTG
     EPLPNDIVLF AMPMCAPYAS LTKFKYKVKL TPGSQKKGKA TKQAMEHFFA SNLKDEKDAS
     KTSGPHRNGE ADDEVQPDVN PIVVQRELMR CIPDNELVNC MVGPVKISAP GLHGPNAGGK
     KGGGKRPSGK PKKKGKK
//