ID W2LWW3_PHYPR Unreviewed; 1875 AA.
AC W2LWW3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Anoctamin transmembrane domain-containing protein {ECO:0000259|Pfam:PF04547};
GN ORFNames=L917_02283 {ECO:0000313|EMBL:ETM01091.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM01091.1};
RN [1] {ECO:0000313|EMBL:ETM01091.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETM01091.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI677825; ETM01091.1; -; Genomic_DNA.
DR EnsemblProtists; ETM01091; ETM01091; L917_02283.
DR VEuPathDB; FungiDB:PPTG_07323; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR Pfam; PF04547; Anoctamin; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 165..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 358..378
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 399..420
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 440..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..490
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 946..971
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1072..1095
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1107..1132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1214..1234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1323..1346
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1358..1379
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 938..1392
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1468..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1530..1549
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1663..1844
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1482..1517
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1698..1712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1815..1834
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1875 AA; 209932 MW; 0358280B702FE908 CRC64;
MSRQRSEANV TTPPVSGSDS FSSRAPISSR ADAKYSTLIS ILEVSIVCSI VFATSKWIQR
ILKSCAWPSI EALAEMKVDG ASAGRKPWRY YYVMVFQLSG NSVAPDKLQE MTEMTAAIEQ
REEKYLRKVA ARNAAHAAAM EAERKAQEEK KPTMISHVAC VLRRLFLLSI ILLLLTAAVG
CTLYWKYDEH DRVSQKLVNV VIVSMLLLLL KDIGGWVVAH KRSVNGARVL FVVGFALIIA
LALLLDEIVI VRRSHSKLRE ALARSEDSLS QDMIEVILNG GAIPSLVQRF VFDAPSVFLQ
WISVHCSSAK LEYTSVAIDR REFFSPLWDD TEKACVNDIL RICVQVDEAI ESIIIGELVM
ISLQVLLTGM FLIVYGPVVS DKSKRRRKLS SPKVNASSFS DLFTALTRLL VFGAASFGVL
NTAASTDLLH FCSIADFHSL FTWVMVICLL SGISAMLAAL FIGCGWKQQV AGVLLVIAVC
SEIFMLGEFF KLAARLIGPD TNQTQLRELR QVYIKASAQT CSSIERWISH VCVGMNSSEE
PAEFDFSCQH EFVALLMVTF NFTNSYLSWS IGVKLVLLVQ ILLPPLRQAI ENMLSSVCCV
SRNELTTMTV KTIIQESSPP LDYEEVLEVY LRSLRVRDPD RMAAEREAFE KEWSSRTGRV
LSDVRTPRIV VSSSDFSAIV RTLMLRRLTA ICKLDVSLSV SEDGQLLLVR ISASDNLLLA
TSCETESYRL QFADAIDPGR SFWRDKKEVN TDQKVLDANT VKHKLKILLA ENAMSPKEAV
WFLGESLARV SARIHALSRI SRVSKGLIRC HNSAPAFASY SPNIQRQFIY KKYPHKLDIP
DTYRRSTVLR TVDCIRVTRR IIDAEFDTNN AIASGLLSSF HCLHSSSRFD FNSRSALASS
WINFWSPTHL PGEFYPDDHA ILNLIGRIAP FRQPLRDVKD YFGEKIGFYF AWLAFYAKMM
MIPAIIAIVA ITSETKHSVM ISLWDYYIPP TYIQGGSTEV GKIDTTIPLP ELLLGVLVIV
WSFSLAKLWE RRSVWYQLQW DIAAKTDSFQ RYNADHGIEY TRSLCSSAQR QLVSWLCVLV
LGGVNLLVTL TVLLSQGLLV DVWGEKVAVL SSCICQALLI QWNGACIPYV APTLSKWENP
YYSRDHHGYQ RSFVAKLFAL QLVNTFSGLI LLMLSGVGGL ALPVQFLTPL IPLYMSYSAR
IEGHVGVFIQ METLLIAIFA VQLSIRAFLI LSALRRFHII QRGDQRKEHE EETMLSPYPG
PGKDYAQVVM QIGLIIMFSS VCPLLPMLAL IDCAVKIRQN ALELCCIRQR PEPEEYDVEP
DLWASYMLLM VKLSVPVALS LALFTVDNFA DISIERRIGY WLIGVLCFWL GAQLLWFLIP
RESRAVEEAR ARNIFQVERY FGHAEVHEQK TPPKDTNEKR VEDEDINLQE ATPSVEHSLH
HYEERLELLH RLNVALRKRD DIGGTVSLAN MTVSTPDDQE AQTSEGMKER THSVSAEEFV
PFDDEDKPQH RDSKDSEEMI VGYFRPVRSV WPPPAQRPAQ QEGIGGDEAP AIDIMEPSEE
PKGSIYSELP VEGATIGENI DERIASAAES GGESAPPVSP VLLSKLFTRM PTFPSTFMPS
SSSEEVDAAL LPSTSPFVSA SLTQADIEPG VFAPTDAEII NRESVNDDDL LEEKEDVSLS
TTDAAVESPR RSFLSRIRSR QVKSSISDSN KDSQVEAGER ALLRQLSPRL SSLPRKSKRL
SSKVSGSEES KSESSSVREP PAPKRLSNLF KRAQSPSTRT TPPSEPPPIV TNREAEDTTV
DPVAPRHDQF AFLSDTHEEQ SSLSIQRRTS SSNRTRPPSP PPVYTRIDLS GLEAVREAAN
RHQFDFSADE QVWEE
//
