ID W2M0T2_PHYPR Unreviewed; 2009 AA.
AC W2M0T2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=C2 domain-containing protein {ECO:0000259|PROSITE:PS50004};
GN ORFNames=L917_00416 {ECO:0000313|EMBL:ETM03354.1};
OS Phytophthora parasitica (Potato buckeye rot agent).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4792 {ECO:0000313|EMBL:ETM03354.1};
RN [1] {ECO:0000313|EMBL:ETM03354.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CHvinca01 {ECO:0000313|EMBL:ETM03354.1};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica CHvinca01.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI677228; ETM03354.1; -; Genomic_DNA.
DR EnsemblProtists; ETM03354; ETM03354; L917_00416.
DR VEuPathDB; FungiDB:PPTG_00384; -.
DR Proteomes; UP000054423; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00030; C2; 2.
DR CDD; cd04011; C2B_Ferlin; 1.
DR CDD; cd04037; C2E_Ferlin; 1.
DR Gene3D; 2.60.40.150; C2 domain; 7.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR037720; C2B_Ferlin.
DR InterPro; IPR037724; C2E_Ferlin.
DR InterPro; IPR012968; FerIin_dom.
DR InterPro; IPR037721; Ferlin.
DR PANTHER; PTHR12546; FER-1-LIKE; 1.
DR PANTHER; PTHR12546:SF33; SPERM VESICLE FUSION PROTEIN FER-1; 1.
DR Pfam; PF00168; C2; 8.
DR SMART; SM00239; C2; 8.
DR SMART; SM01202; FerI; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 8.
DR PROSITE; PS50004; C2; 8.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1898..1915
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1922..1949
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1955..1977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 29..145
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 220..342
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 454..593
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 641..773
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 998..1114
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1151..1284
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1423..1568
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT DOMAIN 1607..1734
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
FT REGION 164..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 397..458
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1748..1815
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 419..443
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..458
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1800..1815
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2009 AA; 226601 MW; 15768A56E14B470C CRC64;
MVKGNQRSFR IAEDHLQWLR WRLRAFGSWW WAPRASERRK RVVMRPSILV CSSPAALFCV
CSSLTLSTDC QAQCGDVVLR TAAKAKTTTP EWTQNFTFGV KKPLGDAVNF KVFGLNARGR
DVLLGSASLQ IETLTPDTQT THKLTLLDAA GKECGELTVE ATYEPKFMAP PRKEGGETPQ
KKPASPKKLS APVSPKTSAV PAKTSAVPAK TDEKPVVDTP TTSIMEEEKE GPSKPPNFYV
VTILEAMGLL ACDGTGIEAT SDPYVRVSCT KNQSQRTKTQ QQTLHPSWRQ RFYFAISPGE
KQLLELTMED SDLLTSDFMG RCVIDLEEFT KRFQGEKQTF WLALEQQPES KDKDLPSDIS
PQRKMNYGNG KICLAIEMQY IDQEISSLEQ GEIDNVTEVP SGRGLRRPGS SDVVDDEGGN
DGNPSEDTNE DVNDGDDDDV DARREEAEAQ RKQREEERQK MLTELSNVQF LSGDYQIRVR
IIEVRDLKPM DANGLCDPVL SVECLGQRQH TVVKQKQLSC VFDEYLYFNF RKLDKETVQQ
GSIKISVFDA DGPGSSANRS AISRALDDLI GFFSVDIPYV YFQPDHELKR KWVALVGSGT
TNSDSIQGYV LLSLVVLGPE DKMKLYDPAE DKDPDEHLVK SKADINSMVL VPPRVTQKLS
FLVITIYRAE ELPDMDYSMM MHGGIDGYVR AYFAGQDVLE TKKVTVKGSE NLAVPFNQEL
WFPVLLPTMS DNIFISMWDW DMTTADQLVA NILQPFSFKQ VQRYPNQFKH IWANLYGPPV
GYDTVSAPLQ LMQNHPAHAS TYRGRLLLSL RVEDGLQSVN DEAHVRNLLN TSISPSMKRY
TLRAALFYGT EIPVFTSKTN WNRNTRMSLK ISMGRHCVES SRAHNVSGIC HFNQYIDIMD
VELPADLDQV PDIFVHLVRK TMNESRCICF ARFKAQDLFC QDPEALKTIE PPHWVVLNED
KVLDELRDHD FTGNVLMNLR LEDAEQKGRK EEEVAQQWRK YASTTVQYMK YVLFIHVFQG
KCLPSTDYDG LLDPYVKVAC VGSEGQVSTR MSTRDPCFYE TVVLDVELPQ NERFLPKVSL
QVYDWDRYDA DDYVGGLKFS LVDFPQMSSS EYSKIRASGE YSAPRPKWYP IYYEKPGDTQ
GELLLSFDLI KKDTPGVIVE PPESIRPPAE EAFIEIMCLG CRGLQPTGFM PINTPFAKFE
VGEITKTNQP KFTNPSSKPS SRNPNFLQRI VVPVKMPLDS LFAPRLNITV YDQLLGGFYK
PVIGVCSVDL SKKMPLSNGE PNPLYIEESS KNVAHGSNPY VDYEDDLSTF PGTVPSDVLT
SRSPSAAAGK TQSKTKKIGI AGMCSSGSFG IYDEDDDELP HYMHQREIVE GELEDTLKSP
FETYALFRGA TSSQDGCNSN EHSADTYRPV GKFKGIVRVL KSRDDPPLFD LDQFLNPQPY
LVRVYVLDAL NLHPKDANNR CDPYLRVSLG DGRRREQMFN DRDNYQPETL TPKFHKMYEF
KADLPGASEL KLELFDYDFF AIPTLPTGLS KALSTAVGST VDGDDFVGAT LIDLEDRWFD
AKWQELGLSP ERAERRKPLE VRPLFAPSST LPQGSVRLWV DILTGAEMNV VRPLDISLPP
PQVFEVRVIV YKAKNVTAGD FTDLSDLFVK CWLQNRDDKS QSTDTHWRAK HGRASFNWRM
KFDVELPLDP EKEADRGYLH FQMWDRDVVY DDCLADAVVD LTSFLKTAFK TKQAVNVFAK
PKPVRIRGSE SMPYEGASRR SGYSATEDAR FSSPRDEVVI SISEEGQGSD KKPLLSREGA
DIDDDEETES EDVDADMENA ESLVKSFMHR LGMGEDPEDA SWLTMTTRDS HTGDRIRAGE
LLVSVEILPK HLADVRAAGL GRGEPNNFPF LPEPADRLHL SAMWNPCYVL EALMGPKYYR
AFASFFLCTL FILLVLFAGP LINVLLTLFE LVPNPIGLIL FFVALALLMG TLFYLLYRCR
RAIIRVSGGD DFNSSKRGKS RRKTRRVLR
//
