ID W2PHM2_PHYPN Unreviewed; 1032 AA.
AC W2PHM2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_18042 {ECO:0000313|EMBL:ETN00347.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN00347.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN00347.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN00347.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KI669639; ETN00347.1; -; Genomic_DNA.
DR RefSeq; XP_008914359.1; XM_008916111.1.
DR AlphaFoldDB; W2PHM2; -.
DR STRING; 761204.W2PHM2; -.
DR EnsemblProtists; ETN00347; ETN00347; PPTG_18042.
DR GeneID; 20186970; -.
DR VEuPathDB; FungiDB:PPTG_18042; -.
DR OMA; PIMNNLY; -.
DR OrthoDB; 91569at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00055; EGF_Lam; 1.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR013111; EGF_extracell.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR030392; S74_ICA.
DR PANTHER; PTHR13029:SF18; MYELIN REGULATORY FACTOR HOMOLOG 1; 1.
DR PANTHER; PTHR13029; UNCHARACTERIZED; 1.
DR Pfam; PF07974; EGF_2; 1.
DR Pfam; PF13884; Peptidase_S74; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS51688; ICA; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00076};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..29
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 30..1032
FT /note="EGF-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004821494"
FT DOMAIN 40..79
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 220..254
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 890..994
FT /note="Peptidase S74"
FT /evidence="ECO:0000259|PROSITE:PS51688"
FT COILED 973..1021
FT /evidence="ECO:0000256|SAM:Coils"
FT DISULFID 69..78
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 244..253
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1032 AA; 110549 MW; 7E365106DBCC26B2 CRC64;
MTDNQTMAKF PSWTRITLAI FFCIHLLLAG GQFVRAVELK GTHCPGQGSQ CSQHGVCAIN
RQGEHVCNCQ WGYTSPDCSI KMCPYGANPT SSQQEDKTIS LRITTNGGAS ITGGALAITF
QAHTVDFEMP LEQVTSEVCT SIFRRFQNLG ELTCKQVHFY GSSSATFDIT LHTFPTFPIM
NNLYYHNGNP PVSEFWCDAT NVQLSSPSGA VQCVFESIND VNVKSYEECS GHGDCNAETG
ICACHEGYYG DHCGKNKDDE DVLVAPALGP LFKGNVLHLS ATRGLSSDFQ IVRADVGGQA
VFTMNGRGDT TWHRGSLQLR EGGLYMSGGA LQLQKDSTFE MKDGRARLQD TSLHLQLQMA
TSASTGGAAL LNVERLSAAS TSELSTLPDY MRISHPKGPI LRVSGAGQTV IHSGGLEILK
GGLRLERGGI QVLSDGIKVM SGGLDVQSGN LAVRSGTLSL KNGQTTLTAP AGPVLLLQRD
GTDGTSHSRP LIEARGSRSS ESKVFEVLDS GSTVVHSGGL HVLAGGVTIE SGGQTIMSGG
LRVASGGIQV ESGSLTTRDG FSIEDGGLTV KTEQVNGKAL HVASPNANFA GALLSFDLSN
HHLHTPPFRI IEALKPTDSE SRTTQTESVF SVDSLGNLET HGDVTTTRGG RIIANGALVS
QAQAVFSSVQ LRASNNLVIP STNSYVQITN DGVASPNTAR IDCEHAYAGQ LLVIQNDDEQ
PLGGELNVAA GAAAIFVFDG GVWRPLTAAV FDTSSLTGVK TLEAENDLNL GEITLSVQSV
QVAGQRAGFV AVYGKGGVLE QHGSLRFDAT SGTFSAEKIE VQRMRGSIDM SESELRGVEI
IGGHISSVNM TAIEMVEVQG ELFVEDEAFF GASVTVDGQV MGSGAYVDAS DERFKCDIHQ
IANASEVVAQ LRGVEYAYNS AEFPDKFPHD GQRELGFIAQ EVEKVAPQVV STDADGFKYV
AYARLMPVVV EALKREQQRA DESDKRIQQL ETEMSDLKRS LQAQQEMFQR LQQQFEEQRD
SYIDPEPLQQ VQ
//
