ID W2PPH8_PHYPN Unreviewed; 1174 AA.
AC W2PPH8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=3'-5' exonuclease domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PPTG_16801 {ECO:0000313|EMBL:ETN02169.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN02169.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN02169.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN02169.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669619; ETN02169.1; -; Genomic_DNA.
DR RefSeq; XP_008912552.1; XM_008914304.1.
DR AlphaFoldDB; W2PPH8; -.
DR STRING; 761204.W2PPH8; -.
DR EnsemblProtists; ETN02169; ETN02169; PPTG_16801.
DR GeneID; 20185863; -.
DR VEuPathDB; FungiDB:PPTG_16801; -.
DR OMA; WAMASPH; -.
DR OrthoDB; 54208at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd04332; YbaK_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR Gene3D; 3.90.960.10; YbaK/aminoacyl-tRNA synthetase-associated domain; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR015003; DUF1853.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR InterPro; IPR036754; YbaK/aa-tRNA-synt-asso_dom_sf.
DR InterPro; IPR007214; YbaK/aa-tRNA-synth-assoc-dom.
DR PANTHER; PTHR47765; 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47765:SF2; EXONUCLEASE MUT-7 HOMOLOG; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF08907; DUF1853; 1.
DR Pfam; PF04073; tRNA_edit; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR SUPFAM; SSF55826; YbaK/ProRS associated domain; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT DOMAIN 874..977
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|Pfam:PF01612"
FT DOMAIN 1068..1163
FT /note="YbaK/aminoacyl-tRNA synthetase-associated"
FT /evidence="ECO:0000259|Pfam:PF04073"
FT COILED 763..790
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1174 AA; 132943 MW; CAC0F37E22B6033A CRC64;
MSSSGDVCSR LPSVLSMPKV VRDLLWTVTS PHLLSDDRFP VLPAEFGVEA LKFDVVTDWL
NALVQDPTPL LTFLQETTSN GRSLALGVYF STLLEFWLRF CPHFGTEKMA IGKQVVSSTN
RTVGQLKFLF RCNFQNGKQR DFHVESSVKF FLLNPIDSNT GENCTGKHVN GDIGNVPLEQ
YVGPHLGENL AWRAQEVDRK LAMRRGESVR TWLEETYSTN VQSHIVLRGY LFEPLTHFVS
TLETSIAHDW YFHRNPAKVT TELKTCLNPN IATDHLRGWW TTDMETDLPA KVRANQATIG
ESRFVILPKL HWLCPVVALE DKTSGQVIVE SNNRLDIPEV EALTLDELII FVREHFQKVT
ASTETNKSGG VAMPLLVAEI VRYPKNVKDG NQHWYEISRG FILDPKCWDP SPLCHEPVRF
RRTLRNDAAG TGEREYGSRR FDCADEGFIK PDVNEAAAGE EKRHHFTDPA STNPRNLCQE
LVSVLSAGDV LFTHADLKRS TRELLLWRRL NCTGVGEESS YIRSCLAFLI FGVNRDDESK
HTSRVGYLLL DVYDGLNREF ESDIPTESSS QECLDWVTLL TEVARGSERW EFLNLVLRAI
DLTLNSADEM KWGGPEKSSQ FSFLDKLLAA RNSRWNSVVV EVIRVFRIGK TTADGHRIQN
IFAELVKQHD WQNAERLATV VQDHGMIQTL FKHLSLLNMT KALKRLQKVA VGLQSANDSI
LTQQSADLMA NDTIPSYLLG QPINHAKNLS LNKVEKFELK WKYVDCLEEI EEVVRRLKKQ
ELNVLNAEDE NSVVRNMLVG IDCEWRPQFL MKEQTSTSNG TEIADPDDLS NEDLEGLSIY
QLAVGDIVYV VDVQVLGVVA AAPLRFIWRP LSPLMLIGFC VSSDIQRIKN SFPELEELQS
NKERATPLLL ELKQLALFRH VPAKHWGLSR LYRECLGEKV DKEQQCSDWG NRPLTTSQLK
YAAKDAYVVQ RLSLHLLADV HFVKDEHYSV NERVREFMKR FDASRSFSHA WTLTSALQPL
GKQHVKAALQ AYGLEARFLK YDKNEQEGLI VKSIALLVRR EKQVNAPRRV EYVVAVLALD
RSIDMHALGA LLEADSEDIS LADQVALVRV FGYSRGCLGP IGLREQQATQ IILDNYLQAE
EYLLCGAGKA DEVYAIAPDQ LIEVVGALVA RISR
//
