ID   W2Q962_PHYPN            Unreviewed;      1114 AA.
AC   W2Q962;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 40.
DE   RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN   ORFNames=PPTG_11140 {ECO:0000313|EMBL:ETN09094.1};
OS   Phytophthora parasitica (strain INRA-310).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN09094.1, ECO:0000313|Proteomes:UP000018817};
RN   [1] {ECO:0000313|Proteomes:UP000018817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG   The Broad Institute Genome Sequencing Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA   Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA   Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA   Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA   Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA   Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RL   Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ETN09094.1, ECO:0000313|Proteomes:UP000018817}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=INRA-310 {ECO:0000313|EMBL:ETN09094.1,
RC   ECO:0000313|Proteomes:UP000018817};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; KI669586; ETN09094.1; -; Genomic_DNA.
DR   RefSeq; XP_008905655.1; XM_008907407.1.
DR   AlphaFoldDB; W2Q962; -.
DR   STRING; 761204.W2Q962; -.
DR   EnsemblProtists; ETN09094; ETN09094; PPTG_11140.
DR   GeneID; 20180706; -.
DR   VEuPathDB; FungiDB:PPTG_11140; -.
DR   OMA; ANYHEFC; -.
DR   OrthoDB; 118714at2759; -.
DR   Proteomes; UP000018817; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR044189; XPO4/7-like.
DR   PANTHER; PTHR12596; EXPORTIN 4,7-RELATED; 1.
DR   PANTHER; PTHR12596:SF2; EXPORTIN-7 ISOFORM X1; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018817}.
FT   DOMAIN          28..94
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          586..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        590..613
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1114 AA;  125431 MW;  793AEAEAF553AEAC CRC64;
     MDANQLRELE TLCRVLYESG NEAERSHAQQ AVLILQSSAE YIPQCQYVLD NSSSPYALLV
     ASTSLTKLIT SHWNNFTTPQ RVDIRNYVLG YLAQKGPTLE KFVTTSLIQM VCRLTKYGWF
     DDEQHREIVA EVTKFLQATV DHCVIGLQIL SELVTEMNLP VAGRNITFHR KIAVSFREDS
     LFRIFQVALT SIKQLQMHNI RGASPQQEAR MGDQALSLLI KCLSFDFIGT NPDESSEETG
     SLQVPTSWRS VIQDPDTLQL LFDFYKTTNP PNTSKCLEAL MLFASVRRNL FSPDKERSVY
     LANLLKGICA ILRAQEGLSD QQNYHEFCRL IGRLKSNYQL SELMKTESFQ EWMDLTPDFT
     IKSFRQWQWS ANSTHYLLAL WARLVAALPY VRADSVPGSP NSGAVNFLDT RIPQVIQAYL
     QSRLDSAEQC ALDDTLDNPL DDEGGLYEQL EKLPTLCHFN YRQTGEYIVS VLDPILNQYA
     KACSILDQNG GAAIAPQQQQ LQSMENQAAW LVYAIGAIIG GQTYSSTSTE GDELVDADLS
     QRVFRAMQLT EHRIIASGGQ TKPSVHFELS LLYYFSSFRK SYIGEQHGMP SAPTPSSSMQ
     PASAGSASSP IMAPSESAMS SKHKAYLRMF ERLGLGDHTV VVNMMVTKVG NNLKFWGEME
     VVISKTLALF FEVASGYSSG KLLLGLETVQ YLIGNHTAEE FPFLAVPANT RHRTTFHSTI
     ARLIFTTAFD ESSERFERFM EPIENVLNQL LQTPNYRVPE VREAVIGVCR DLRGIIQQTH
     NRRTYSCIFD LLYPAYFPVF VRAADELYDH PAVTTALLKF LQELAYNKAQ RVTFDQSSAS
     GILLFRELSS VVVAYGRRIQ PVPAGKNPYG DKYKGVALCL GIMYRALGGN YVNFGVFQLY
     NDKSLENALE IALQLVLSIP HEDLMHYPKV KNAYFFFLEI LFRNQLASVV ALEDGIFRQL
     VQSLHEGMNS YDLAIAAQCA TAVDHLASLY FQEMKKKRDT PVKHALRAHV QGSPNMWSTL
     LAALLDILVY GEANSQWALS RPILSLTLCS EEALTNYQQQ LSSSQPPENR AQIEEAFAAL
     FADVRPNLEA ANRDKFTQRL GQFRNTLRSF LTIQ
//