ID W2RC60_PHYPN Unreviewed; 1499 AA.
AC W2RC60;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Anaphase-promoting complex subunit 4-like WD40 domain-containing protein {ECO:0000259|Pfam:PF12894};
GN ORFNames=PPTG_02170 {ECO:0000313|EMBL:ETN22135.1};
OS Phytophthora parasitica (strain INRA-310).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=761204 {ECO:0000313|EMBL:ETN22135.1, ECO:0000313|Proteomes:UP000018817};
RN [1] {ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genome Sequencing Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Young S.K., Zeng Q., Gargeya S., Fitzgerald M., Haas B.,
RA Abouelleil A., Alvarado L., Arachchi H.M., Berlin A., Chapman S.B.,
RA Gearin G., Goldberg J., Griggs A., Gujja S., Hansen M., Heiman D.,
RA Howarth C., Larimer J., Lui A., MacDonald P.J.P., McCowen C.,
RA Montmayeur A., Murphy C., Neiman D., Pearson M., Priest M., Roberts A.,
RA Saif S., Shea T., Sisk P., Stolte C., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RL Submitted (DEC-2011) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ETN22135.1, ECO:0000313|Proteomes:UP000018817}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=INRA-310 {ECO:0000313|EMBL:ETN22135.1,
RC ECO:0000313|Proteomes:UP000018817};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica INRA-310.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KI669562; ETN22135.1; -; Genomic_DNA.
DR EMBL; KI669562; ETN22136.1; -; Genomic_DNA.
DR RefSeq; XP_008891427.1; XM_008893179.1.
DR RefSeq; XP_008891435.1; XM_008893187.1.
DR STRING; 761204.W2RC60; -.
DR EnsemblProtists; ETN22135; ETN22135; PPTG_02170.
DR EnsemblProtists; ETN22136; ETN22136; PPTG_02170.
DR GeneID; 20172421; -.
DR VEuPathDB; FungiDB:PPTG_02170; -.
DR OrthoDB; 2954862at2759; -.
DR Proteomes; UP000018817; Unassembled WGS sequence.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR024977; Apc4-like_WD40_dom.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR46362; GEM-ASSOCIATED PROTEIN 5; 1.
DR PANTHER; PTHR46362:SF1; GEM-ASSOCIATED PROTEIN 5; 1.
DR Pfam; PF12894; ANAPC4_WD40; 1.
DR Pfam; PF00400; WD40; 4.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 2.
DR PROSITE; PS50082; WD_REPEATS_2; 4.
DR PROSITE; PS50294; WD_REPEATS_REGION; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018817};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 255..277
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 409..450
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 458..515
FT /note="Anaphase-promoting complex subunit 4-like WD40"
FT /evidence="ECO:0000259|Pfam:PF12894"
FT REPEAT 700..743
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 744..784
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1458..1478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1458..1472
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1499 AA; 165418 MW; 16AD00F0135B7F3B CRC64;
MVASAATKVD AAAGDVAHGS TGSWHGKDHL RLLPPSANWY CSKICDWGRS DVLGLLFAFG
AKNSVFIYQA MNDGDAGVKV AFVAQLVRSK RDRRVTAVQF FTDTTGELRL VCGGEEGSVQ
IWDVASLTMI EQHKKHKAEV MAVTVSAALD ANFVVAGDRQ GSISTWERDA GKVSVFVPIS
GDGIHSMAIS PHDKALVAVG YRSGVLCLVD AARGTVRHRL DGHDQEVQCV AWKAIVNTID
GQDGRDGTSH REVWLASSSR DKTIKVWKIT SSEAPALDQL LRLPTGKQGM SFTQTKQLWL
PVAWSLKDKV SRKHCLWSGS FDGSLFRWEW DAVKTEAPRD KNRRVSCKPA VVKGGHNRML
FSITMVSPTL ATEGDVVSML TVSLDRELRL WKDNGSSKNL AAATCLETLV GFGGHAYSVS
YNTETGLVAA GVGDQTIRLW NLAIEATSAS DYQCDLLWKG LQSKVTCVRW HPFQHSVLAY
GMEDGRIGVY NIQTKKYTHF RTSHSSEVQQ LQWIVVKARK SDGLDDEDNS FLESIKQLEA
AQADGQSLEE ALIAQGGQRD RKDTGDEVKV VLWSSDATGH LIESNSDAVD QKSREIIDNC
VAFEWDEQCD VVAIGRSNGA VEVMEICGST GDNSVVHRFH EHLESVTCVG WSNGTNANLL
ASGGQEGKLF VYNCGKMSSN VSLWSSGSGV AQENRLVGSF DGHSNKITAL RWCPDLAQNR
LASTSADGSV QVWNTTSLQR EAHFNHHIGR VLSLDWVSPY TLVTGGEDQT LRLWDYREQK
KDASPKHKKY GKVKQPQQVD TVATLPPIEP VAVQNGQEAN IAVLHEAYES KVTNSKQKNK
NMMVFHTEKK LNPVEIASVC YKVAGVGHEA EKNPVDCLLA HIDRTSLRDF FTSESKRFRD
EREWESLANT LLIQGNIIEA LRVVAKEGAL TPTWLSHAPM GGMDVWREMT NLYAHQLDAQ
GDKKEAAFHF VSIGKIRAAV ACLVSGEAYK EALALIRSRL GPNDPLLHDT LWKYSDFLTK
RGRHGEAALV LLNIDSVKAK TRAIHLLVNT GDISYIKAAL DVLLASVQSQ AEAAETDQKT
DSEELAFPAS FFLSIAGNAI AKSHFAVAET AGQLLRSRLA GTSSASHRLT WCLLCILKNL
DEHQLRQCKP DAVKDEGVTN QVDNLLSDAP ASAREFFQFL TRIREGDENI FRLYSRVVCS
NVLGNIQEEN LKRWMVTRTN KFWFKVLSAC RRCGYWFDGD GEARIQEAQD LLVEANCFSD
INTASSQQGT DNTIALSLVM AQKILRFVID AMSTSFIGAL EHMREVFQLL TEDEMSKETD
ETNTEGTTSH QSVSDLQVNV MTLLYPCGFA SPNELPQCGE LAEEHLDTLV LWSSMLLSQC
RITLAASVST TKSCTDDSEQ KLESMIRSLL HLLKIELLDD EAAIPSNRGL MDPSNQAQIE
KLMSEVLAAI RQLPDEPAIL EKRTDDSDGD EGLSSKQALI IDANDMRSRL TWSEDKVNQ
//
