ID W2RLX3_9EURO Unreviewed; 840 AA.
AC W2RLX3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=PH domain-containing protein {ECO:0000259|PROSITE:PS50003};
GN ORFNames=HMPREF1541_08301 {ECO:0000313|EMBL:ETN37310.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN37310.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN37310.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN37310.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB822724; ETN37310.1; -; Genomic_DNA.
DR RefSeq; XP_008720842.1; XM_008722620.1.
DR AlphaFoldDB; W2RLX3; -.
DR STRING; 1220924.W2RLX3; -.
DR GeneID; 19975640; -.
DR VEuPathDB; FungiDB:HMPREF1541_08301; -.
DR eggNOG; ENOG502QRAF; Eukaryota.
DR HOGENOM; CLU_006465_0_0_1; -.
DR InParanoid; W2RLX3; -.
DR OrthoDB; 1363487at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR CDD; cd13311; PH_Slm1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR046868; BAR_4.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR046869; SLM1/RGC1-like_PH.
DR InterPro; IPR043453; Slm1_PH.
DR PANTHER; PTHR31941:SF1; ACTIVATOR OF SKN7 PROTEIN 10-RELATED; 1.
DR PANTHER; PTHR31941; CYTOSKELETAL SIGNALING PROTEIN SLM1; 1.
DR Pfam; PF20400; BAR_4; 1.
DR Pfam; PF20399; PH_20; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752};
KW Transferase {ECO:0000256|ARBA:ARBA00022676}.
FT DOMAIN 415..520
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 1..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 589..688
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..840
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..34
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..92
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 105..119
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 534..548
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 619..636
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 666..688
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 762..820
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 840 AA; 90964 MW; 8BF52D1B6B8D8C84 CRC64;
MSRPQTPASG GYSSSAAPIN ELDRTQSRLS YAGSTAPAGT GLEHSAGAPR PTSALSQNED
FHGDAHPGAG ERSSVLQRSN SQMSQSATAI SRGGTLKKKA SLRGTSLKRS NSRKSSYAGS
VRSMKLGEKE KYESEESNSA FYCPVPTVGN PTELLANRFQ SWRKVLKDLI NYFRDLHKSY
EVRSKTLLSA SNIINNTTIP SNFVTSGGLG DAAYILRDFH KQAISEANKA KDLENEVIMQ
LTGLRSDLQQ KIKEIKSLSG DFKNSVDKEQ EQTKRAIRAY QEALGLVDHD ASATTGKGDP
FIVKMNVDRQ VERQIDEENY LHRAYLNLEA SGRELESIVV GEIQKAYTVL AGIMRREADD
FYDTAEKLRE GPLAISKDME WDTFVTNNHQ MVDPRNPVRQ VEHITYPGKD HPAALEVRSG
MLERKSKYLK NYTPGWYILS PTHLHEFKSA DRLASQSPVM SLYLPEQKIG SHSEPGSSSH
KFMLKGRQSG SMHRGHSWVF RAETYDTMLA WYSDVKELTE KTGEARNDFV RRTHARSMSG
SSLKAPSIGG SSEGALEDDE ADRQAFAGEQ SIRGNSFADG MTTATGATGL AEKSSEAGWR
PQQRPSPGGR FPSDLNVQRG LQAPVSPSSG GSSDRDVIAH ASTLPGSAIP FNNAQEKPSE
LPQPAAAAGQ QYTQGAHPNL FPQSAGAENQ SQYGDWMAPM AAGAAGGAVI GSASHHHQNK
QETEPARPVI ENIDNSERQM DAASPIPEYG TSSPPIPIPI PITATTTTTE PPTGAASTAP
TASTNTDINT ISTQTTAPTE YSSRPGLEKT LTSKSVSTIS DLHMPGEFPR NTGTTTTPTA
//
