ID W2RUC3_9EURO Unreviewed; 547 AA.
AC W2RUC3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Amidase domain-containing protein {ECO:0000259|Pfam:PF01425};
GN ORFNames=HMPREF1541_04317 {ECO:0000313|EMBL:ETN40042.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN40042.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN40042.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN40042.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB822720; ETN40042.1; -; Genomic_DNA.
DR RefSeq; XP_008716885.1; XM_008718663.1.
DR AlphaFoldDB; W2RUC3; -.
DR STRING; 1220924.W2RUC3; -.
DR GeneID; 19971656; -.
DR VEuPathDB; FungiDB:HMPREF1541_04317; -.
DR eggNOG; KOG1212; Eukaryota.
DR HOGENOM; CLU_009600_9_2_1; -.
DR InParanoid; W2RUC3; -.
DR OrthoDB; 731186at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.90.1300.10; Amidase signature (AS) domain; 1.
DR InterPro; IPR023631; Amidase_dom.
DR InterPro; IPR036928; AS_sf.
DR PANTHER; PTHR46072; AMIDASE-RELATED-RELATED; 1.
DR Pfam; PF01425; Amidase; 1.
DR PIRSF; PIRSF001221; Amidase_fungi; 1.
DR SUPFAM; SSF75304; Amidase signature (AS) enzymes; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752}.
FT DOMAIN 74..534
FT /note="Amidase"
FT /evidence="ECO:0000259|Pfam:PF01425"
FT ACT_SITE 130
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 205
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
FT ACT_SITE 229
FT /note="Acyl-ester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR001221-1"
SQ SEQUENCE 547 AA; 59814 MW; 386E0FF405E69DB2 CRC64;
MAPWQEIAAT RQTAVLDSIP TKWRLPSKPD TSTKNVQHIP RTCGLITPDQ LHITEQTTVE
LAAQLSRGKL TSVEVTEAFC ARAAVAHQCV NCLTGFYYEE AMGKAAEADA ILKETRKPVG
PLHGVPIAIK DIFNIKGKRG TMGLVAWQDK EWGVDASIVT LLKAAGAIQF ASTTMPQGGM
MLQTVSPLWG RTLNPFNTDF AAGGSSGGDG TLLALRGSPF CPSTDIGGSI RAPAAFNGLY
GIRPTADRIP KFGMISTAPG QTSIKVSCGP NCHSVGDLKL VTKLLFSHTD YIGFDPTAVP
LPWKEVQSKQ KLVLGMLKTD GVVTPQPPIL RALAEVAEKL KAAGHEVVEI EPPIDLWEAA
LVTWKLYFQT GATELRALVS SADEPLEPQL AWYLDTFAIK ELTVPELFQT NLKQAAIKRH
FADFWAYTKQ LTWNGSPIDG LICPSAPSAS YPHDFPVWWG YFSIWNLLDY PSAILPLKDF
SISEEKDPKD TFYNPIETNP FDKMNADIYN PKLWAGMPVS IQIVQQQFAD EELLSVTEVV
DKVVNSS
//
