ID W2S725_9EURO Unreviewed; 551 AA.
AC W2S725;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA-directed RNA polymerase III subunit RPC3 {ECO:0000256|RuleBase:RU367076};
DE Short=RNA polymerase III subunit C3 {ECO:0000256|RuleBase:RU367076};
GN ORFNames=HMPREF1541_10979 {ECO:0000313|EMBL:ETN43848.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN43848.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN43848.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN43848.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific core component of RNA polymerase III which synthesizes small
CC RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|ARBA:ARBA00025127,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex
CC consisting of 17 subunits. {ECO:0000256|ARBA:ARBA00011206,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU367076}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta chain family.
CC {ECO:0000256|ARBA:ARBA00006835, ECO:0000256|RuleBase:RU367076}.
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DR EMBL; KB822717; ETN43848.1; -; Genomic_DNA.
DR RefSeq; XP_008713870.1; XM_008715648.1.
DR AlphaFoldDB; W2S725; -.
DR STRING; 1220924.W2S725; -.
DR GeneID; 19978318; -.
DR VEuPathDB; FungiDB:HMPREF1541_10979; -.
DR eggNOG; KOG2587; Eukaryota.
DR HOGENOM; CLU_023294_0_0_1; -.
DR InParanoid; W2S725; -.
DR OrthoDB; 1429291at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0003697; F:single-stranded DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:InterPro.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 3.
DR InterPro; IPR013197; RNA_pol_III_RPC82-rel_HTH.
DR InterPro; IPR008806; RNA_pol_III_Rpc82_C.
DR InterPro; IPR039748; RPC3.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR12949:SF0; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC3; 1.
DR PANTHER; PTHR12949; RNA POLYMERASE III DNA DIRECTED -RELATED; 1.
DR Pfam; PF08221; HTH_9; 1.
DR Pfam; PF05645; RNA_pol_Rpc82; 1.
PE 3: Inferred from homology;
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|RuleBase:RU367076}; Nucleus {ECO:0000256|RuleBase:RU367076};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU367076}.
FT DOMAIN 7..66
FT /note="RNA polymerase III subunit RPC82-related helix-turn-
FT helix"
FT /evidence="ECO:0000259|Pfam:PF08221"
FT DOMAIN 152..375
FT /note="RNA polymerase III Rpc82 C -terminal"
FT /evidence="ECO:0000259|Pfam:PF05645"
SQ SEQUENCE 551 AA; 62438 MW; 193530D8605720BB CRC64;
MAEHLNQLCC LIIEDTYGSF LSHIFKQVAT YGRLPAGQIA QRCHLLLRQA KAGLATLIQL
RLVQHHSVEG FSTYQANLTN AYDLLRTGKL AQLAHAQYGS IAGLVIEVLA AKGFASVKDL
EAAVLQALEQ SSDRETPYQN GSKASVKVQD TLRRLANDQF MSKLSIGHLQ IPHDARQDAE
AGHELVTAGG QRGENLRADR LSKVQEEMER RLDTYVSADM IEAALDVPNG EAVGATPQQE
LYLCLNYVRV IKDVRNATVT QHVNKTLGRT SARLTTAVLK QIELQSPPFE RSPNVRTEEQ
LVVLSRLLDD TRRMPLQNGT HGTNGHHDED TAMTNGANED EYLDQEDLES GLDLVSSGPY
PFIRRDENTA WWYIDRYQVA IWLRDREILN LISARIGPTG MRLVRMLIDK GKLDEKLLQE
MGLLSAKEMR QALAELQTMG LTELQEVPRE PQRQPNRTIF LWFYDALRAR DLLLGQLYKS
MARCYQRLQV VERERMRATL DKIERDDVKD RIEEVVVGAE KVALEQFQAK ERWLMGEIAR
LDESVALLRD M
//
