ID W2S9R5_9EURO Unreviewed; 779 AA.
AC W2S9R5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=Ras-GAP domain-containing protein {ECO:0000259|PROSITE:PS50018};
GN ORFNames=HMPREF1541_09243 {ECO:0000313|EMBL:ETN45412.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN45412.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN45412.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN45412.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KB822712; ETN45412.1; -; Genomic_DNA.
DR RefSeq; XP_008712140.1; XM_008713918.1.
DR AlphaFoldDB; W2S9R5; -.
DR STRING; 1220924.W2S9R5; -.
DR GeneID; 19976582; -.
DR VEuPathDB; FungiDB:HMPREF1541_09243; -.
DR eggNOG; KOG2128; Eukaryota.
DR HOGENOM; CLU_009455_0_0_1; -.
DR InParanoid; W2S9R5; -.
DR OrthoDB; 24454at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05132; RasGAP_GAPA; 1.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF17; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030752}.
FT DOMAIN 187..403
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 779 AA; 89248 MW; 7864F8F4D7696F3B CRC64;
MSVATMLQPT SRGSASTASS FEPVSRTNTY SSHDGARSIR QSKRVSMTAL YVSMSAKDKD
LEISDDLARA QRTLRDLKSK ISTQSKKNFV LEKDVRYLDS RIALLIQNRM ALEEQNEVAS
RLDDATELQE GSFPNDEKTQ KYGNLFFMLQ SEPKHIAHLC RLVTMAEIDS LLQTVMFTIY
GNQYESREEH LLLTMFQSVL THQFENTPEY SSLLRQNTPV SRMMTTYTRR GPGQGYLKEV
LAEKINSLTE LADVDLEINP LKVYETMVKQ IEDDSGSLPE DLPRSVTAEF AAENAQVQAI
IAPRLKMLTE IAEGFLSTIM EALDEVPYGI RWICKQIRNL SRRKYPDAQD SAICVLIGGF
FFLRFINPAI VTPKSYMLIE RVPEEKPKRT LTYIAKMLQN LANKPTYAKE PYMARLQPFI
QRNKDRVNKF LLDLCEVQDF YESLEMDNYV ALSKRDIELQ ISLNEVYATH ALLEKHAKEL
ATDPSSHLGT ILAEFGPAPP QLPRKENRAI NLPLYSRWET SFDEFTQALD ITQDEVYFME
AKSSFVQIMR SLPQNASIMR RPLRLEAVAK AAGQMKDPVM VRKGIRCMEL LNSLLEMGAL
DRADDYAALR DEVEQELAHL GSLKEKVQEE TNKLDDVYKT IRDHNAYLLS QLDTYKSYLH
NVRSQSEGTK RGKEVKVKEL GPYKFTHAQL EKDGVIVRSN VPENRRSNIF FMFRSPLAGT
FVISLHYKGR ARGLLELDLK LDDLLEMQKD GQEDLDLEYV QFDVSKVLAL LNKRFARKK
//
