ID W2SBV5_9EURO Unreviewed; 437 AA.
AC W2SBV5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=RING-CH-type domain-containing protein {ECO:0000259|PROSITE:PS51292};
GN ORFNames=HMPREF1541_00279 {ECO:0000313|EMBL:ETN46095.1};
OS Cyphellophora europaea CBS 101466.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Chaetothyriomycetidae; Chaetothyriales; Cyphellophoraceae; Cyphellophora.
OX NCBI_TaxID=1220924 {ECO:0000313|EMBL:ETN46095.1, ECO:0000313|Proteomes:UP000030752};
RN [1] {ECO:0000313|EMBL:ETN46095.1, ECO:0000313|Proteomes:UP000030752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 101466 {ECO:0000313|EMBL:ETN46095.1,
RC ECO:0000313|Proteomes:UP000030752};
RG The Broad Institute Genomics Platform;
RA Cuomo C., de Hoog S., Gorbushina A., Walker B., Young S.K., Zeng Q.,
RA Gargeya S., Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phialophora europaea CBS 101466.";
RL Submitted (MAR-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KB822711; ETN46095.1; -; Genomic_DNA.
DR RefSeq; XP_008710807.1; XM_008712585.1.
DR AlphaFoldDB; W2SBV5; -.
DR STRING; 1220924.W2SBV5; -.
DR GeneID; 19967618; -.
DR VEuPathDB; FungiDB:HMPREF1541_00279; -.
DR eggNOG; KOG3053; Eukaryota.
DR HOGENOM; CLU_026793_0_0_1; -.
DR InParanoid; W2SBV5; -.
DR OrthoDB; 2730627at2759; -.
DR Proteomes; UP000030752; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011016; Znf_RING-CH.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR46283:SF2; AT07234P-RELATED; 1.
DR PANTHER; PTHR46283; E3 UBIQUITIN-PROTEIN LIGASE MARCH5; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51292; ZF_RING_CH; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030752};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 348..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 390..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 28..102
FT /note="RING-CH-type"
FT /evidence="ECO:0000259|PROSITE:PS51292"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 292..329
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 315..329
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 437 AA; 48600 MW; 40D7209B8E1C00AB CRC64;
MSSDTSEPVL LEKPNEEGTP RPSPLSRQST LTPKKCWICI CDATEDDPTN PPTWRTPCAC
NLTAHEACLL DWVADLENPK KKDRPRDGVI RCPQCKTEIK ITRPKSYILE FTKALDRGLA
LAIYPGLGTA ALGTIFAGCW LHGFMSVYVF FGPDHAVRIF NNATNHQRLA YGLVPINLIF
SRTNFADSVL TVGTFFLLST QIDPNRFEID MTLWPPLPST VFICLPAIRR AYNWLYFKTF
ADLNRKWLEA VQPASIQPVE GQEQNLADLA NQNDPVDGEM VFELEVRIGE DEDNDNEEDE
HVPAADDGAQ QGEGPGAANN GNDNGNGNAH VHHQVQEIVE GIGISTTILG ALVFPTVAAG
MGRLLTYALP KSWMSNANMM NGRPGLLRDQ WGRSVVGGAI FIVLKDALLL YSRWKRAQTH
KMRSIVDYDK KAQKYLM
//
