ID W2SJX9_NECAM Unreviewed; 227 AA.
AC W2SJX9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=DSHCT domain protein {ECO:0000313|EMBL:ETN69910.1};
GN ORFNames=NECAME_05096 {ECO:0000313|EMBL:ETN69910.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN69910.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI669035; ETN69910.1; -; Genomic_DNA.
DR RefSeq; XP_013292137.1; XM_013436683.1.
DR AlphaFoldDB; W2SJX9; -.
DR STRING; 51031.W2SJX9; -.
DR EnsemblMetazoa; NECAME_05096; NECAME_05096; NECAME_05096.
DR GeneID; 25345128; -.
DR KEGG; nai:NECAME_05096; -.
DR CTD; 25345128; -.
DR OMA; SEICFDS; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3380.30; -; 1.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF08148; DSHCT; 1.
DR SMART; SM01142; DSHCT; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 75..224
FT /note="ATP-dependent RNA helicase Ski2/MTR4 C-terminal"
FT /evidence="ECO:0000259|SMART:SM01142"
SQ SEQUENCE 227 AA; 26008 MW; 1DF16D7DB397E25B CRC64;
MEKYSASLST NANSFIFRVT ELFGRVFILI KNLRERVRVE RQISNLKYSL SVDALQLSDE
YQNRIEVLKK LGYVDRTGMV TFKGRVACEI HHQELLITEL ILSKKLHERS PAEVAAMLSA
TTCQYKGGDG PKFEKDSVFE KLKEDVQSTN GMIENVASSF RVRIGDVGDE LRYDLMQVVY
HWAGGMKKIS EICFDSRMFV SPYVASWKWK SAPESSLVQR SARMDNQ
//
