ID W2SKV2_NECAM Unreviewed; 279 AA.
AC W2SKV2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=ribose-5-phosphate isomerase {ECO:0000256|ARBA:ARBA00011959};
DE EC=5.3.1.6 {ECO:0000256|ARBA:ARBA00011959};
DE AltName: Full=Phosphoriboisomerase {ECO:0000256|ARBA:ARBA00029734};
GN ORFNames=NECAME_15364 {ECO:0000313|EMBL:ETN69357.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN69357.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribose
CC 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step
CC 1/1. {ECO:0000256|ARBA:ARBA00004988}.
CC -!- SIMILARITY: Belongs to the ribose 5-phosphate isomerase family.
CC {ECO:0000256|ARBA:ARBA00008088}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI669121; ETN69357.1; -; Genomic_DNA.
DR RefSeq; XP_013291584.1; XM_013436130.1.
DR AlphaFoldDB; W2SKV2; -.
DR STRING; 51031.W2SKV2; -.
DR EnsemblMetazoa; NECAME_15364; NECAME_15364; NECAME_15364.
DR GeneID; 25355390; -.
DR KEGG; nai:NECAME_15364; -.
DR CTD; 25355390; -.
DR OMA; ACHVQEK; -.
DR OrthoDB; 5232260at2759; -.
DR UniPathway; UPA00115; UER00412.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0004751; F:ribose-5-phosphate isomerase activity; IEA:UniProtKB-EC.
DR GO; GO:0009052; P:pentose-phosphate shunt, non-oxidative branch; IEA:InterPro.
DR CDD; cd01398; RPI_A; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.50.1360; -; 1.
DR InterPro; IPR037171; NagB/RpiA_transferase-like.
DR InterPro; IPR004788; Ribose5P_isomerase_type_A.
DR NCBIfam; TIGR00021; rpiA; 1.
DR PANTHER; PTHR11934; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR PANTHER; PTHR11934:SF0; RIBOSE-5-PHOSPHATE ISOMERASE; 1.
DR Pfam; PF06026; Rib_5-P_isom_A; 1.
DR SUPFAM; SSF75445; D-ribose-5-phosphate isomerase (RpiA), lid domain; 1.
DR SUPFAM; SSF100950; NagB/RpiA/CoA transferase-like; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:ETN69357.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
SQ SEQUENCE 279 AA; 30490 MW; 29B3A3C89096F5D6 CRC64;
MHSIRFANSL YTSECFSSIT VAQARFLAAS IRRMVSSTEL SPIEKAKRQA AYTCAEKNIA
SGCRLGVGSG STVKYLVEYL ETAVKSGKLQ NIVCVPTSFL TKKWLLDAGL TVSDLDATPE
LDVCIDGADE VDAHFTCIKG GGGCLAREKI VQHAAKKFFV IADSSKESVN LGEHYNHVPI
EVLPFAASCL LRSLPRTEGG TAQMRMATKK CGPVITDNNN YVVDWAFEKN KPRDWKEIQL
RLANTPGIVE TGLFIGVVDK VYFAYPDGSV KELEAKKKP
//
