ID W2SPE0_NECAM Unreviewed; 229 AA.
AC W2SPE0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE SubName: Full=B-box zinc finger {ECO:0000313|EMBL:ETN70567.1};
GN ORFNames=NECAME_14683 {ECO:0000313|EMBL:ETN70567.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN70567.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI668929; ETN70567.1; -; Genomic_DNA.
DR RefSeq; XP_013292794.1; XM_013437340.1.
DR AlphaFoldDB; W2SPE0; -.
DR STRING; 51031.W2SPE0; -.
DR EnsemblMetazoa; NECAME_14683; NECAME_14683; NECAME_14683.
DR GeneID; 25354710; -.
DR KEGG; nai:NECAME_14683; -.
DR CTD; 25354710; -.
DR OrthoDB; 2939799at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd19773; Bbox2_TRIM23_C-IX_rpt1; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR47156; PROTEIN CBG20824; 1.
DR PANTHER; PTHR47156:SF10; RING-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Signal {ECO:0000256|SAM:SignalP}; Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..229
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004826070"
FT DOMAIN 125..166
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 143..170
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 229 AA; 25556 MW; 6C718E05B3C7C8A4 CRC64;
MTSYLIFLAC IIRSSMAASD ASVRCGHTIC QGCAQSICRP GVSYIVCPFD RVSTPVTGGD
VRLLKKNFAL LELIERIQQS CNEGEKRNAL PLKVADNYID KCSSGSLLSR KVDRYARDRL
LGIDCDEDPC HTAVLFCTVC ESHLCERCAD SSHDTNVLSK HRRIPLSEKP ASTASCRVHN
SYPIEFVCKE ESCSNKNGLM CIFCRDYGLH KVCCSLRILL NFMCPRLRV
//
