ID W2SPK8_NECAM Unreviewed; 473 AA.
AC W2SPK8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Zinc finger, C2H2 type {ECO:0000313|EMBL:ETN70766.1};
GN ORFNames=NECAME_14540 {ECO:0000313|EMBL:ETN70766.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN70766.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI668897; ETN70766.1; -; Genomic_DNA.
DR RefSeq; XP_013292993.1; XM_013437539.1.
DR AlphaFoldDB; W2SPK8; -.
DR EnsemblMetazoa; NECAME_14540; NECAME_14540; NECAME_14540.
DR GeneID; 25354567; -.
DR KEGG; nai:NECAME_14540; -.
DR CTD; 25354567; -.
DR OMA; IRCDESG; -.
DR OrthoDB; 2874526at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR CDD; cd18186; BTB_POZ_ZBTB_KLHL-like; 1.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24394:SF29; GM08392P; 1.
DR PANTHER; PTHR24394; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00651; BTB; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00355; ZnF_C2H2; 3.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 18..90
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT REGION 176..202
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..202
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 53809 MW; D569BB8D29272F9E CRC64;
MSLQTDNILG NFGFNFDFDA CINVRSNEPV LAHRLVLSSA STRFRNLLAA DQQESPIAKI
DIDLREIPNS INAFKAMLNG LYTGELNFAL ADHSEILAVA RHCEVPTIES KLLAASHEPA
PFVALLPQHK FPTIASNPPW QTYLHTLLAL YMQPGLLAST FGGALLPCHT AALHPPSTPA
DDSRASVDES SSPRTTPISY NEKIVPNDDK EGWCRNKKYI EKVDSGFMCT VCRKVYGRYN
SVSYHVTIYH RNPPIRCDES GCQFSTREAR YIHFHKYYRH HIPLPESIDL GSRKCPFCRH
VSKSPAMLEK HIARHVPERK EKPSESFNCD QCMYRWEKVE EAINPNVVAV PEVAAHVLKM
GSKLLTYYCL LLPKLTITTY YYLNYLFRIL VNQVMQPEQH MYGQNGNVAR APQAIRTFCR
GVPEKNTMFI VSVCVQFSTC THFAHRLLTF TVRIHAKRGE HRATNCRSNR AYY
//
