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Database: UniProt
Entry: W2ST00_NECAM
LinkDB: W2ST00_NECAM
Original site: W2ST00_NECAM 
ID   W2ST00_NECAM            Unreviewed;       161 AA.
AC   W2ST00;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   SubName: Full=Redoxin family protein {ECO:0000313|EMBL:ETN72874.1};
GN   ORFNames=NECAME_13712 {ECO:0000313|EMBL:ETN72874.1};
OS   Necator americanus (Human hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC   Necator.
OX   NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN72874.1, ECO:0000313|Proteomes:UP000053676};
RN   [1] {ECO:0000313|Proteomes:UP000053676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24441737; DOI=10.1038/ng.2875;
RA   Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA   Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA   Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA   Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA   Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT   "Genome of the human hookworm Necator americanus.";
RL   Nat. Genet. 46:261-269(2014).
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DR   EMBL; KI662740; ETN72874.1; -; Genomic_DNA.
DR   RefSeq; XP_013295101.1; XM_013439647.1.
DR   AlphaFoldDB; W2ST00; -.
DR   EnsemblMetazoa; NECAME_13712; NECAME_13712; NECAME_13712.
DR   GeneID; 25353740; -.
DR   KEGG; nai:NECAME_13712; -.
DR   CTD; 25353740; -.
DR   OMA; TDDYKHE; -.
DR   OrthoDB; 3073590at2759; -.
DR   Proteomes; UP000053676; Unassembled WGS sequence.
DR   GO; GO:0045494; P:photoreceptor cell maintenance; IEA:InterPro.
DR   GO; GO:0007600; P:sensory perception; IEA:InterPro.
DR   CDD; cd02964; TryX_like_family; 1.
DR   Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR   InterPro; IPR029519; RdCVF2.
DR   InterPro; IPR012336; Thioredoxin-like_fold.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   InterPro; IPR013766; Thioredoxin_domain.
DR   PANTHER; PTHR46762; NUCLEOREDOXIN-LIKE PROTEIN 2; 1.
DR   PANTHER; PTHR46762:SF1; NUCLEOREDOXIN-LIKE PROTEIN 2; 1.
DR   Pfam; PF13905; Thioredoxin_8; 1.
DR   SUPFAM; SSF52833; Thioredoxin-like; 1.
DR   PROSITE; PS51352; THIOREDOXIN_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT   DOMAIN          19..160
FT                   /note="Thioredoxin"
FT                   /evidence="ECO:0000259|PROSITE:PS51352"
SQ   SEQUENCE   161 AA;  17832 MW;  C67317B22A55329A CRC64;
     MALPGNLRIL LAFSHFGPIP MADLLKGVKI QKKDGTSANA EDDKVVGLYF SAHWCPPCRQ
     FTPVLKDFYG ELEDGEEFEI VFVSFDRSES DLKEYMEECH GDWYCIPFGS PQIQELATKY
     SVSGIPALVI IKADGTEVTK NGRNDVQSKA PRAALSAWKA A
//
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