ID W2SXV9_NECAM Unreviewed; 116 AA.
AC W2SXV9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Peptidase S8 pro-domain domain-containing protein {ECO:0000259|Pfam:PF16470};
GN ORFNames=NECAME_12954 {ECO:0000313|EMBL:ETN74470.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN74470.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KI660358; ETN74470.1; -; Genomic_DNA.
DR RefSeq; XP_013296697.1; XM_013441243.1.
DR AlphaFoldDB; W2SXV9; -.
DR STRING; 51031.W2SXV9; -.
DR EnsemblMetazoa; NECAME_12954; NECAME_12954; NECAME_12954.
DR GeneID; 25352982; -.
DR KEGG; nai:NECAME_12954; -.
DR CTD; 25352982; -.
DR OrthoDB; 5401294at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.850; Peptidase S8, pro-domain; 1.
DR InterPro; IPR032815; S8_pro-domain.
DR InterPro; IPR038466; S8_pro-domain_sf.
DR PANTHER; PTHR42884:SF13; NEUROENDOCRINE CONVERTASE 2; 1.
DR PANTHER; PTHR42884; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN-RELATED; 1.
DR Pfam; PF16470; S8_pro-domain; 1.
DR SUPFAM; SSF54897; Protease propeptides/inhibitors; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825}.
FT DOMAIN 2..54
FT /note="Peptidase S8 pro-domain"
FT /evidence="ECO:0000259|Pfam:PF16470"
SQ SEQUENCE 116 AA; 13586 MW; 6C477347CC42C8DD CRC64;
MLGEVLGSDH EFHFVQPALS HARTKRSIGH HAKLHNDDDV IHVEQLTGYK RAKRGYRPLA
ERLQSQFDFS PVQSPTDPLY NYQWYLNAEA SYDFSSNDPF PYPRYTDDWF NSHGTR
//
