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Database: UniProt
Entry: W2SYG4_NECAM
LinkDB: W2SYG4_NECAM
Original site: W2SYG4_NECAM 
ID   W2SYG4_NECAM            Unreviewed;       343 AA.
AC   W2SYG4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-SEP-2017, entry version 15.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETN73936.1};
GN   ORFNames=NECAME_13306 {ECO:0000313|EMBL:ETN73936.1};
OS   Necator americanus (Human hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Strongylida; Ancylostomatoidea; Ancylostomatidae; Bunostominae;
OC   Necator.
OX   NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN73936.1, ECO:0000313|Proteomes:UP000053676};
RN   [1] {ECO:0000313|Proteomes:UP000053676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24441737; DOI=10.1038/ng.2875;
RA   Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K.,
RA   Martin J., Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V.,
RA   Minx P., Warren W.C., Wang Q., Zhan B., Hotez P.J., Sternberg P.W.,
RA   Dougall A., Gaze S.T., Mulvenna J., Sotillo J., Ranganathan S.,
RA   Rabelo E.M., Wilson R.K., Felgner P.L., Bethony J., Hawdon J.M.,
RA   Gasser R.B., Loukas A., Mitreva M.;
RT   "Genome of the human hookworm Necator americanus.";
RL   Nat. Genet. 46:261-269(2014).
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DR   EMBL; KI660400; ETN73936.1; -; Genomic_DNA.
DR   RefSeq; XP_013296163.1; XM_013440709.1.
DR   GeneID; 25353334; -.
DR   KEGG; nai:NECAME_13306; -.
DR   CTD; 25353334; -.
DR   Proteomes; UP000053676; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR019424; 7TM_GPCR_Srsx.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   Pfam; PF10320; 7TM_GPCR_Srsx; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053676};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     20     47       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     54     76       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    113    136       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    148    172       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    192    214       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    235    260       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    272    289       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       36    286       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   343 AA;  38925 MW;  0C914D534855D2C7 CRC64;
     MFFEYVRVNA SVIDGFDDRI NYHIVNTVLG VACTVINFVL LAIFVGYRPF RTRYVLLIQL
     CVGDLIYSAA VVLTGFQRIR LYSAATHTLT LPVRTTADCA SEMWLQLKLI GDLLIPVTIF
     WMGVERFTAI SFPLFYRMNV DGKPLKCFVV PLLSGIFVLA SVVFALFTAK YYSHRTYYHC
     GRKATFGEGF STFLYISNIF CNVFSTTLNA AAYIKARTMT KNVHRAQRHV DIIRYYLLIS
     VLSTVLVSLP NTIALFQVYV KSVSDAISKP SVWMQTINSG IHFFVYLALN REFRRRAFHL
     LRPNSGKMEN SIKYPESHLD GADSTLIHNG KAVAMDVISY PKS
//
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