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Database: UniProt
Entry: W2T4M8_NECAM
LinkDB: W2T4M8_NECAM
Original site: W2T4M8_NECAM 
ID   W2T4M8_NECAM            Unreviewed;       242 AA.
AC   W2T4M8;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-SEP-2017, entry version 16.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ETN76985.1};
GN   ORFNames=NECAME_00511 {ECO:0000313|EMBL:ETN76985.1};
OS   Necator americanus (Human hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Strongylida; Ancylostomatoidea; Ancylostomatidae; Bunostominae;
OC   Necator.
OX   NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN76985.1, ECO:0000313|Proteomes:UP000053676};
RN   [1] {ECO:0000313|Proteomes:UP000053676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24441737; DOI=10.1038/ng.2875;
RA   Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K.,
RA   Martin J., Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V.,
RA   Minx P., Warren W.C., Wang Q., Zhan B., Hotez P.J., Sternberg P.W.,
RA   Dougall A., Gaze S.T., Mulvenna J., Sotillo J., Ranganathan S.,
RA   Rabelo E.M., Wilson R.K., Felgner P.L., Bethony J., Hawdon J.M.,
RA   Gasser R.B., Loukas A., Mitreva M.;
RT   "Genome of the human hookworm Necator americanus.";
RL   Nat. Genet. 46:261-269(2014).
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DR   EMBL; KI660200; ETN76985.1; -; Genomic_DNA.
DR   RefSeq; XP_013299212.1; XM_013443758.1.
DR   GeneID; 25340555; -.
DR   KEGG; nai:NECAME_00511; -.
DR   CTD; 25340555; -.
DR   Proteomes; UP000053676; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
DR   InterPro; IPR019424; 7TM_GPCR_Srsx.
DR   InterPro; IPR000276; GPCR_Rhodpsn.
DR   InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR   Pfam; PF10320; 7TM_GPCR_Srsx; 2.
DR   PRINTS; PR00237; GPCRRHODOPSN.
DR   SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR   PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053676};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     12     34       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     46     65       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM     85    104       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    125    146       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    166    194       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    206    223       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       28    142       G_PROTEIN_RECEP_F1_2.
FT                                {ECO:0000259|PROSITE:PS50262}.
SQ   SEQUENCE   242 AA;  27731 MW;  56471A57BA7B56C7 CRC64;
     MSNQTVMEMV PMPMVFTTLA FSIVGLLGNG IIVLATFASP SLKNRCNILI CILATADFVV
     CGYLIQLRIQ MLKNWYFQKN SECFAHSIYG LFALNIQAGM GLILGIDRLF AVTLSVRYSR
     LPKRLYFVMM MFVLSYAALM TFYGYLDSSA QNTHEQSVER IRRLLYSLSI VMGVYTSTWF
     LTVIALLVTQ LFSLSPSLIG EINQQLGWLV IINASTNFFI YMWRAPEYRY SLILSPMWMW
     IE
//
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