ID W2T683_NECAM Unreviewed; 118 AA.
AC W2T683;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Prefoldin subunit {ECO:0000313|EMBL:ETN77134.1};
GN ORFNames=NECAME_11247 {ECO:0000313|EMBL:ETN77134.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN77134.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC -!- SUBUNIT: Heterohexamer of two PFD-alpha type and four PFD-beta type
CC subunits. {ECO:0000256|ARBA:ARBA00011695}.
CC -!- SIMILARITY: Belongs to the prefoldin subunit beta family.
CC {ECO:0000256|ARBA:ARBA00008045}.
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DR EMBL; KI660190; ETN77134.1; -; Genomic_DNA.
DR RefSeq; XP_013299361.1; XM_013443907.1.
DR AlphaFoldDB; W2T683; -.
DR STRING; 51031.W2T683; -.
DR EnsemblMetazoa; NECAME_11247; NECAME_11247; NECAME_11247.
DR GeneID; 25351276; -.
DR KEGG; nai:NECAME_11247; -.
DR CTD; 25351276; -.
DR OMA; MFVAVPM; -.
DR OrthoDB; 26461at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016272; C:prefoldin complex; IEA:InterPro.
DR GO; GO:0051082; F:unfolded protein binding; IEA:InterPro.
DR GO; GO:0006457; P:protein folding; IEA:InterPro.
DR Gene3D; 1.10.287.370; -; 1.
DR InterPro; IPR002777; PFD_beta-like.
DR InterPro; IPR009053; Prefoldin.
DR PANTHER; PTHR20903:SF0; PREFOLDIN SUBUNIT 1; 1.
DR PANTHER; PTHR20903; PREFOLDIN SUBUNIT 1-RELATED; 1.
DR Pfam; PF01920; Prefoldin_2; 1.
DR SUPFAM; SSF46579; Prefoldin; 1.
PE 3: Inferred from homology;
KW Chaperone {ECO:0000256|ARBA:ARBA00023186};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT COILED 67..115
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 118 AA; 13682 MW; 42D4305C6D90B5B1 CRC64;
MADEELKKAF QDLQFKTNET KSLIAQGEVT KKVNTQKQRM SELSAASIAE VPSDLSVYRS
VGRMFLLTTK EAEIERHNKE ALEFKEKVEA FTKQKEYLQR GLEEAERNLR EMVQARRA
//
