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Database: UniProt
Entry: W2TA62_NECAM
LinkDB: W2TA62_NECAM
Original site: W2TA62_NECAM 
ID   W2TA62_NECAM            Unreviewed;      1484 AA.
AC   W2TA62;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   03-JUL-2019, entry version 27.
DE   SubName: Full=FAD dependent oxidoreductase {ECO:0000313|EMBL:ETN78915.1};
GN   ORFNames=NECAME_02779 {ECO:0000313|EMBL:ETN78915.1};
OS   Necator americanus (Human hookworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Strongylida;
OC   Ancylostomatoidea; Ancylostomatidae; Bunostominae; Necator.
OX   NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN78915.1, ECO:0000313|Proteomes:UP000053676};
RN   [1] {ECO:0000313|Proteomes:UP000053676}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=24441737; DOI=10.1038/ng.2875;
RA   Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K.,
RA   Martin J., Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V.,
RA   Minx P., Warren W.C., Wang Q., Zhan B., Hotez P.J., Sternberg P.W.,
RA   Dougall A., Gaze S.T., Mulvenna J., Sotillo J., Ranganathan S.,
RA   Rabelo E.M., Wilson R.K., Felgner P.L., Bethony J., Hawdon J.M.,
RA   Gasser R.B., Loukas A., Mitreva M.;
RT   "Genome of the human hookworm Necator americanus.";
RL   Nat. Genet. 46:261-269(2014).
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DR   EMBL; KI659684; ETN78915.1; -; Genomic_DNA.
DR   RefSeq; XP_013301142.1; XM_013445688.1.
DR   GeneID; 25342817; -.
DR   KEGG; nai:NECAME_02779; -.
DR   CTD; 25342817; -.
DR   KO; K17509; -.
DR   OrthoDB; 137947at2759; -.
DR   Proteomes; UP000053676; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.30.1360.120; -; 1.
DR   Gene3D; 3.50.50.60; -; 1.
DR   InterPro; IPR006076; FAD-dep_OxRdtase.
DR   InterPro; IPR036188; FAD/NAD-bd_sf.
DR   InterPro; IPR032503; FAO_M.
DR   InterPro; IPR013977; GCV_T_C.
DR   InterPro; IPR006222; GCV_T_N.
DR   InterPro; IPR029043; GcvT/YgfZ_C.
DR   InterPro; IPR006578; MADF-dom.
DR   InterPro; IPR027266; TrmE/GcvT_dom1.
DR   Pfam; PF01266; DAO; 1.
DR   Pfam; PF16350; FAO_M; 1.
DR   Pfam; PF01571; GCV_T; 1.
DR   Pfam; PF08669; GCV_T_C; 1.
DR   Pfam; PF10545; MADF_DNA_bdg; 1.
DR   SMART; SM00595; MADF; 1.
DR   SUPFAM; SSF101790; SSF101790; 1.
DR   SUPFAM; SSF51905; SSF51905; 1.
DR   PROSITE; PS51029; MADF; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053676}.
FT   DOMAIN     1304   1399       MADF. {ECO:0000259|PROSITE:PS51029}.
FT   REGION     1413   1434       Disordered. {ECO:0000256|MobiDB-lite:
FT                                W2TA62}.
SQ   SEQUENCE   1484 AA;  167248 MW;  ADC6C028BB1365B5 CRC64;
     MPPPPSNISF SKCAEKRQED NVNEGRILEV YGSGRTRRVV LAPNGHNNEG HPSAAFYAQI
     ADQAGITEDY LESIAGVLLS LTHKTKNRQL RITSLSLAAY VALKMGRYHY AADLAHKMID
     EEESIGNCSM TASMYLMECM VSSGPFDIAL KVMSVDGTER QAGECGSYPI WAVINRCIVL
     CANRKYHEAE NLYKEIRAST STNDLYERSV LALGIFIYSK LNRAPDAFRL IEELRNIQDE
     EDEQIVGEGG RSNTAEDPLI VLARILCCVL TLFYMESTLW NVSRLSGTIF LQYAYEFSKF
     TSSADVVVCG GGIAGTSVAY HLAKRGKRVC LFEKDAVGCG GATGVSGGLV TAPIFFQHPT
     KRHLARRSLD LYTELAHLGR FKFTKCGRVY MASSTANEIM LRRMYSRGAI YSDDVELIDC
     PSEMLSRWPF LQTEDIQLAL FSPEDVALDP VALCQELAKQ AQLAGAQIFE SCAVEEVLLG
     DERQVYAVKT GSGLVETPRF VDASGIWTGT VLTKTLPFRH IQTAAYPCTY TYIHSAKLPT
     SSVSDTTPIF NDLDGKIMIR ATAFKTLCAG FLIDGIRPLA RHSTSQGVWT HPEPDWDLFG
     SSLEKLLHRC PMIGEIDHGD LICGMEAYTP DKAPAVGESS QAHGYYVMNG LNGQGLSMAG
     GLGELMADWI CDGIPEIDVA HLDVGRFLEL HANSQYLMER VPEIAAMTYS NMYHSHQFHT
     ARNLRMSPIY HQLRDAGAVF GEIMGYERPL WFEQYPKSER NALFQGQDPL IGRPVWFDSV
     AIEYEACRER VALIDMSSFT KFDVMGPDVV KFLQYLCSAN IDRPVGTTIY SGMQHERGGY
     VTDCTLSRLS ETSYFIVAPT IQQERCMTWM KYWIDKMKVN VHIQDVTGMY TALDVVGPSS
     RYLMADVTEM SMSTTDFPNF RCQEINIGMA TGIRAISVTH CGELGWVIYI PNEVAQNVYE
     RLVEAGREYS LLHAGYYTLR QLRIEKFYVY WGQDIDATVT PVECGRSFRV DFQPDEYEAL
     RHAFRVDFTK DFIGKPALVK QLERGVSKRF VQLLVDNHDK DTDPWPQGGE TLFRDGKPVG
     CTTTAAYGFT LGCHVCTAYV VNKEFGISAD FLNRGRYELD IAGKRFPVRV NLHSPSLPMI
     SSEHPLHYRP TQYNGTRVDK NLYICCAKII IGKCKTKTNK AFTEDVDFYA YVRSRSADAR
     QMTADRDAAR DASGPRAWTA HVVTTPRTCP LRDALQLLYG ELDMVGTNDA DEEVFQKPPS
     IGEEHNLQTL HAAEHQWVGS HQQQSVSTPV QHHGSMITDE VRFSIIDAVY LRPGIWDCQR
     EKTVGPSRKE LFVEVTNLIN QQNQLDPELT PEEVEKQWKN LKDTYVKTRK KLSYNSDSIP
     VTPKWKFYSS LMFLDDLFNV HRNIQKRRID EVSGSSQTLV SGKRIPPPPE DQEEEDEYMA
     FCRSLLHPLR EIAYKDRIQY LKVQKAIRDL LHDAQMDMLL THMR
//
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