ID W2TB70_NECAM Unreviewed; 216 AA.
AC W2TB70;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Ras family protein {ECO:0000313|EMBL:ETN79113.1};
GN ORFNames=NECAME_10030 {ECO:0000313|EMBL:ETN79113.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN79113.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI659640; ETN79113.1; -; Genomic_DNA.
DR RefSeq; XP_013301340.1; XM_013445886.1.
DR AlphaFoldDB; W2TB70; -.
DR STRING; 51031.W2TB70; -.
DR EnsemblMetazoa; NECAME_10030; NECAME_10030; NECAME_10030.
DR GeneID; 25350059; -.
DR KEGG; nai:NECAME_10030; -.
DR CTD; 25350059; -.
DR OMA; ECQSRAQ; -.
DR OrthoDB; 8685at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04139; RalA_RalB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005225; Small_GTP-bd_dom.
DR InterPro; IPR001806; Small_GTPase.
DR InterPro; IPR020849; Small_GTPase_Ras-type.
DR NCBIfam; TIGR00231; small_GTP; 1.
DR PANTHER; PTHR24070; RAS, DI-RAS, AND RHEB FAMILY MEMBERS OF SMALL GTPASE SUPERFAMILY; 1.
DR PANTHER; PTHR24070:SF258; RAS-RELATED PROTEIN RAL-A; 1.
DR Pfam; PF00071; Ras; 1.
DR PRINTS; PR00449; RASTRNSFRMNG.
DR SMART; SM00175; RAB; 1.
DR SMART; SM00176; RAN; 1.
DR SMART; SM00173; RAS; 1.
DR SMART; SM00174; RHO; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51419; RAB; 1.
DR PROSITE; PS51421; RAS; 1.
DR PROSITE; PS51420; RHO; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
SQ SEQUENCE 216 AA; 24053 MW; 354EB3D9136FC70C CRC64;
MSAQKKASTA QQANAAPVVH KVIMVGTGGV GKSALTLQFM YDEFVEEYEP TKADSYRKKV
VLDGEECSID ILDTAGQEDY SAIRDNYYRS GEGFICVFSI LDMDSFDATT EFREQILRVK
NSDNSIPIVL VGNKADLREE RVVPLEMARQ RAERWGVPYV ETSAKRRENV DKVFYDLMRE
IKRRKGGPMG TSAAGLDHAQ VGGKKKGGLK KLCSIL
//
