ID W2TCK8_NECAM Unreviewed; 217 AA.
AC W2TCK8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=GOLD domain-containing protein {ECO:0000259|SMART:SM01190};
GN ORFNames=NECAME_02790 {ECO:0000313|EMBL:ETN78926.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN78926.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI659684; ETN78926.1; -; Genomic_DNA.
DR RefSeq; XP_013301153.1; XM_013445699.1.
DR AlphaFoldDB; W2TCK8; -.
DR EnsemblMetazoa; NECAME_02790; NECAME_02790; NECAME_02790.
DR GeneID; 25342828; -.
DR KEGG; nai:NECAME_02790; -.
DR CTD; 25342828; -.
DR OMA; YEICISS; -.
DR OrthoDB; 2877372at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR InterPro; IPR009038; GOLD_dom.
DR Pfam; PF01105; EMP24_GP25L; 1.
DR SMART; SM01190; EMP24_GP25L; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..217
FT /note="GOLD domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004826527"
FT TRANSMEM 184..204
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 33..209
FT /note="GOLD"
FT /evidence="ECO:0000259|SMART:SM01190"
SQ SEQUENCE 217 AA; 24982 MW; C7E0E9E111836283 CRC64;
MRILLFLFLN LVNYSNALTF RTRGGRESIV VRIITIDLEA RLTCMYETLE KEMMLELQAD
VTPSSNAPIS MRLTSPTGAF SEWLEGRGEV DFRHITTEDG DYEICISSSR NIRVLLSIYF
KHPEKVGDAL EAELNASLIN RNLEELSRSM GDLIYKIYNA LRFYNLVTVS DEATQRSNSY
YIKVYVISFC IANIIVAILQ VAIVRRMFRV DKSRIRI
//
