ID W2TFG0_NECAM Unreviewed; 407 AA.
AC W2TFG0;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Tropomyosin {ECO:0000313|EMBL:ETN79931.1};
GN ORFNames=NECAME_09502 {ECO:0000313|EMBL:ETN79931.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN79931.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC -!- SIMILARITY: Belongs to the tropomyosin family.
CC {ECO:0000256|ARBA:ARBA00009036, ECO:0000256|RuleBase:RU004515}.
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DR EMBL; KI659280; ETN79931.1; -; Genomic_DNA.
DR RefSeq; XP_013302158.1; XM_013446704.1.
DR AlphaFoldDB; W2TFG0; -.
DR STRING; 51031.W2TFG0; -.
DR EnsemblMetazoa; NECAME_09502; NECAME_09502; NECAME_09502.
DR GeneID; 25349531; -.
DR KEGG; nai:NECAME_09502; -.
DR CTD; 25349531; -.
DR OMA; LELEWEM; -.
DR OrthoDB; 2917119at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR Gene3D; 1.20.5.170; -; 3.
DR Gene3D; 1.20.5.340; -; 1.
DR InterPro; IPR000533; Tropomyosin.
DR PANTHER; PTHR19269; TROPOMYOSIN; 1.
DR PANTHER; PTHR19269:SF45; TROPOMYOSIN-1, ISOFORMS 33_34; 1.
DR Pfam; PF00261; Tropomyosin; 3.
DR PRINTS; PR00194; TROPOMYOSIN.
DR SUPFAM; SSF57997; Tropomyosin; 4.
DR PROSITE; PS00326; TROPOMYOSIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT REGION 112..140
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 223..271
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 313..403
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 407 AA; 46974 MW; F6D60A86D9637D3F CRC64;
MSKVNKEGAQ QTSLLDVLKK KMRQAREEAE AAKDEADEAE AEVAALNRRI VLVEEDLERT
EDRLKIATSK LEEAVNPLQA EAEVAALNRR MTLLEEELER AEERLKIATE KLEEATQNVD
ESERARKSME TRSQQDEERA NFLETQVDEA KVIAEDADRK ARKSLENRVD VDEDRCAELE
TKLREAQALL HETESKSEEV HVVHCALLPP CPFACLVLFP CSKREVARKL AMVEADLERA
EERAEAGENK IVELEEELRV VGNNLKSLEL SEEKALEKED IFADQLRQLD FRMKEPELCC
EQCKWLCFVY SKIVELEEEL RVVGNNLKSL EVSEEKALQR EDSYEEQIRT ISARLKEAET
RAEFAERSVQ KLQKEVDRLE EEKDEADRKN RQLQEELDHL LTELNGV
//
