ID W2TGP7_NECAM Unreviewed; 276 AA.
AC W2TGP7;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Carboxylesterase type B domain-containing protein {ECO:0000259|Pfam:PF00135};
GN ORFNames=NECAME_08695 {ECO:0000313|EMBL:ETN81215.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN81215.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI658822; ETN81215.1; -; Genomic_DNA.
DR RefSeq; XP_013303442.1; XM_013447988.1.
DR AlphaFoldDB; W2TGP7; -.
DR EnsemblMetazoa; NECAME_08695; NECAME_08695; NECAME_08695.
DR GeneID; 25348724; -.
DR KEGG; nai:NECAME_08695; -.
DR CTD; 25348724; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR PANTHER; PTHR43903:SF9; BILE SALT-ACTIVATED LIPASE; 1.
DR PANTHER; PTHR43903; NEUROLIGIN; 1.
DR Pfam; PF00135; COesterase; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..276
FT /note="Carboxylesterase type B domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004826615"
FT DOMAIN 21..87
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT DOMAIN 137..243
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 276 AA; 30118 MW; C6FCCD92CFBF518E CRC64;
MRNTVALILF YCTISFALKG KELSEDVIGY LGIPYAKPPL RDMRFKDSQV LPFDDGGVYT
EWPAGCPGTS IEGRTEDCLF LSLLQLKNIV KKTNTLLIFA NDKLSEKKLA GLVSPNLNIG
LAAIRAGVLG SYGNSSFGVS DVINAVKFLK ENEDVLSIGK ITVWAESFEA EAVASALSEA
GIERAILING NAKTRAAGRD RVSSWTAYKI ATELECDLPS AAQSTDCLRT KSLLELYAAM
EKVSASSLSI FGQDWIYFLN LPKEIPIATR VAYRLR
//
