ID W2TGR9_NECAM Unreviewed; 300 AA.
AC W2TGR9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Collagen triple helix repeat protein {ECO:0000313|EMBL:ETN80381.1};
GN ORFNames=NECAME_09222 {ECO:0000313|EMBL:ETN80381.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN80381.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI659115; ETN80381.1; -; Genomic_DNA.
DR RefSeq; XP_013302608.1; XM_013447154.1.
DR AlphaFoldDB; W2TGR9; -.
DR STRING; 51031.W2TGR9; -.
DR EnsemblMetazoa; NECAME_09222; NECAME_09222; NECAME_09222.
DR GeneID; 25349251; -.
DR KEGG; nai:NECAME_09222; -.
DR CTD; 25349251; -.
DR OMA; GENGICP; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0005581; C:collagen trimer; IEA:UniProtKB-KW.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0042302; F:structural constituent of cuticle; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR InterPro; IPR002486; Col_cuticle_N.
DR PANTHER; PTHR24637; COLLAGEN; 1.
DR PANTHER; PTHR24637:SF421; COLLAGEN-RELATED; 1.
DR Pfam; PF01484; Col_cuticle_N; 1.
DR SMART; SM01088; Col_cuticle_N; 1.
PE 4: Predicted;
KW Collagen {ECO:0000313|EMBL:ETN80381.1}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..64
FT /note="Nematode cuticle collagen N-terminal"
FT /evidence="ECO:0000259|SMART:SM01088"
FT REGION 111..282
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 131..164
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 300 AA; 29615 MW; 604ED79D1BEF0770 CRC64;
METEIKVKML RLVAYASVAL SVLSVLAVSA TVPLLYKYVN YVKRSLNEEV QFCWESGKDI
YEEVQNMRTI PYEGGRLVRQ VYHNQTYESG TEDTSTSDLK CENCCLPGPS GVAGAPGKPG
KPGRSGSPGM PGNPGRPPQP PCSLVTGPPC PSCPPGPPGL PGAQGGPGEP GRAGTPGIPG
EDGVPGPPGP PGLSGESGED GKPGVDGKPG TPAPDVLPIP GLAGKSGRPG APGAPGQPGI
PGGGGSAGAP GPKGSPGLNG LPGDDGPPGM PGPVGPPGQP GARGTCASYC AVDGGVFIDE
//
