ID W2TMZ3_NECAM Unreviewed; 552 AA.
AC W2TMZ3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Ankyrin repeat protein {ECO:0000313|EMBL:ETN82501.1};
GN ORFNames=NECAME_17696 {ECO:0000313|EMBL:ETN82501.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN82501.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI658456; ETN82501.1; -; Genomic_DNA.
DR RefSeq; XP_013304728.1; XM_013449274.1.
DR AlphaFoldDB; W2TMZ3; -.
DR STRING; 51031.W2TMZ3; -.
DR EnsemblMetazoa; NECAME_17696; NECAME_17696; NECAME_17696.
DR GeneID; 25357721; -.
DR KEGG; nai:NECAME_17696; -.
DR CTD; 25357721; -.
DR OMA; MIAAFKM; -.
DR OrthoDB; 1063832at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24171; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED; 1.
DR Pfam; PF00023; Ank; 2.
DR Pfam; PF12796; Ank_2; 1.
DR SMART; SM00248; ANK; 5.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 4.
DR PROSITE; PS50088; ANK_REPEAT; 4.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|ARBA:ARBA00023043, ECO:0000256|PROSITE-
KW ProRule:PRU00023}; Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 8..40
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 41..73
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 74..101
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 456..490
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
SQ SEQUENCE 552 AA; 62437 MW; 83EE6FF84B9CEC32 CRC64;
MDVHRNHVGA PALWAASAAG KFEAVKYLVE HGADIEVANQ HGHTSLMIAA YRQKVDVVKY
LISCGADVNR SSKKGNTAMH DAVEGENLEV CALLLNAGAR LVPDEFGVCP LMCAVMIGAD
WILPMLLEYC ESGEKRRDAL KLLGCTRVDK KMDMVGAIEA WNDALQVPLT DEERKHVEEK
VERFEVAQVY EGHKEIQTLE DIAAIEDSPD AIRLQDGTIH LTTFQSLLIR ERILGGAHAD
VHYYLRFRGA VYSDLGHVDK CYELWSHALI LQQTHLTPLH MSTQTMFQAF LETFLHTLND
RAIHMELAGR RNAPPKQDIV KFVFERVCLE LERLAEWGER PLSDLCNCGE DHVHSCDDEK
KRVVLLGLQL LALMNRLSLP MHEEEEEDDV VYFCRASETV KIDVRRFAEA CRQLKIPLLH
YAVKEIDTVE FDGMPSYFVV ERLLAAGVCV NSKDADGDTA LHVMLKNSHP RMSVVRLLLE
YGAYVLARDA EGKTCFDIIT NRNEHLLQPF SFPMRLGKYI TLKGLAANSV RRNNLAHEQV
IPQDLVYYTQ LH
//
