ID W2TQH3_NECAM Unreviewed; 267 AA.
AC W2TQH3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Chitin binding Peritrophin-A domain protein {ECO:0000313|EMBL:ETN84058.1};
GN ORFNames=NECAME_07085 {ECO:0000313|EMBL:ETN84058.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN84058.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI658036; ETN84058.1; -; Genomic_DNA.
DR RefSeq; XP_013306285.1; XM_013450831.1.
DR AlphaFoldDB; W2TQH3; -.
DR STRING; 51031.W2TQH3; -.
DR EnsemblMetazoa; NECAME_07085; NECAME_07085; NECAME_07085.
DR GeneID; 25347116; -.
DR KEGG; nai:NECAME_07085; -.
DR CTD; 25347116; -.
DR OMA; RCTHVHE; -.
DR OrthoDB; 3058078at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR Gene3D; 2.170.140.10; Chitin binding domain; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR002557; Chitin-bd_dom.
DR InterPro; IPR036508; Chitin-bd_dom_sf.
DR PANTHER; PTHR23301; CHITIN BINDING PERITROPHIN-A; 1.
DR PANTHER; PTHR23301:SF109; PROTEIN CBG16847; 1.
DR Pfam; PF01607; CBM_14; 2.
DR SMART; SM00494; ChtBD2; 3.
DR SUPFAM; SSF57625; Invertebrate chitin-binding proteins; 3.
DR PROSITE; PS50940; CHIT_BIND_II; 3.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 29..84
FT /note="Chitin-binding type-2"
FT /evidence="ECO:0000259|PROSITE:PS50940"
FT DOMAIN 94..132
FT /note="Chitin-binding type-2"
FT /evidence="ECO:0000259|PROSITE:PS50940"
FT DOMAIN 168..222
FT /note="Chitin-binding type-2"
FT /evidence="ECO:0000259|PROSITE:PS50940"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..29
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 267 AA; 28530 MW; 1ED6DC7550468841 CRC64;
MDLMELLQAK PSTTPSAPTS SDYKPPSISS ECTDLPDGTF GSQCGSSFVV CSNGVSYTMS
CPSDLVFDAK KSRCVYPDEC DCVGKPDGLH SLGCIGEFLQ CVDGRTYSLY CPAGLVFVEQ
LGACDVPSAC KPTPKPENVS GPLPYEPVMS PGTGAGNGKR QAIYHHTDNS CKDRPDGVIT
DSDCQPQFTT CLSGTAFVTK CPAGLVYSIA AKLCDYPEAC ERKDYDKPTT APAVVAPPAK
PDVTYQDTAV GSMYQACRVY RYLNFFD
//
