ID W2TRU2_NECAM Unreviewed; 195 AA.
AC W2TRU2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=tRNA-guanine transglycosylase {ECO:0000313|EMBL:ETN84755.1};
GN ORFNames=NECAME_06719 {ECO:0000313|EMBL:ETN84755.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN84755.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI657872; ETN84755.1; -; Genomic_DNA.
DR RefSeq; XP_013306982.1; XM_013451528.1.
DR AlphaFoldDB; W2TRU2; -.
DR STRING; 51031.W2TRU2; -.
DR EnsemblMetazoa; NECAME_06719; NECAME_06719; NECAME_06719.
DR GeneID; 25346751; -.
DR KEGG; nai:NECAME_06719; -.
DR CTD; 25346751; -.
DR OrthoDB; 11459at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR GO; GO:0016763; F:pentosyltransferase activity; IEA:InterPro.
DR GO; GO:0101030; P:tRNA-guanine transglycosylation; IEA:UniProt.
DR Gene3D; 3.20.20.105; Queuine tRNA-ribosyltransferase-like; 1.
DR InterPro; IPR036511; TGT-like_sf.
DR InterPro; IPR002616; tRNA_ribo_trans-like.
DR NCBIfam; TIGR00449; tgt_general; 1.
DR PANTHER; PTHR46064; QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2; 1.
DR PANTHER; PTHR46064:SF1; QUEUINE TRNA-RIBOSYLTRANSFERASE ACCESSORY SUBUNIT 2; 1.
DR Pfam; PF01702; TGT; 1.
DR SUPFAM; SSF51713; tRNA-guanine transglycosylase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 38..193
FT /note="tRNA-guanine(15) transglycosylase-like"
FT /evidence="ECO:0000259|Pfam:PF01702"
SQ SEQUENCE 195 AA; 22350 MW; 24CAF22797B93BA7 CRC64;
MLDYDAPKGS LNKRLAKGIE RSKSFCDYLF GEDEDSAEVD LRGFVHGNEV DLGEIRELVE
ETFAPLPPGK LRFVAGPFDP AMVLHLSKLG FDLFDSSYAV KMAEEAKAIR LADDFPYSSR
FELLDFNVDK YADDYDKLFQ SCECYTCKNY TRMYLRHLTN TKELLGPILL VIHNMMEYHR
MFSLIRTAID DGDAV
//
