ID W2TUI9_NECAM Unreviewed; 463 AA.
AC W2TUI9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=MSP domain protein {ECO:0000313|EMBL:ETN85488.1};
GN ORFNames=NECAME_06355 {ECO:0000313|EMBL:ETN85488.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN85488.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
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DR EMBL; KI657714; ETN85488.1; -; Genomic_DNA.
DR RefSeq; XP_013307715.1; XM_013452261.1.
DR AlphaFoldDB; W2TUI9; -.
DR EnsemblMetazoa; NECAME_06355; NECAME_06355; NECAME_06355.
DR GeneID; 25346387; -.
DR KEGG; nai:NECAME_06355; -.
DR CTD; 25346387; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 16..89
FT /note="MSP"
FT /evidence="ECO:0000259|Pfam:PF00635"
FT REGION 279..379
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 296..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..377
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 52824 MW; D5836A2D987A82DF CRC64;
MSLKVEQCIT SLQSAAAGTT VHRLVSLTRE RIAFKVEISE KSRHYVVYPI EGFIDSGEMV
RLTVRPTTNK FTPANLVIRW AETDDDVVDV LMALRGNGRA GQIIHPLNPR NHCDEVRYPS
ALLKVDDDEW ADARRSWLLV KFGYATVAIR DENVIWKAVS KITEELSSNH IFLEDRPLFC
SLSCLSEKQI VNDIWNHLQA AKPGSYPVLL LIDDYHGRFT NIIKHHFSKH MYIFQLSGEE
VVDIAASSEE RPFIIAILSG WCREFTSLVM QSEEEKLQSS NFSSNLGGAY FPNEEPPDRD
LMRDDQQRDS YGTHGRPPDN PHHIYEEVPN GRHRPHGEYQ DGRYTYSQKW EEQSSTHEEN
LRQSRQGSHE TSPDDSRYAS WDNHSNLDYV WSETSSEEID DCGSSDSTKI ATSHDIELAL
VYARDNRSDG NIVSILRFDS PKTNLSSELS SHYTSLPLLF SIG
//
