ID W2TX99_NECAM Unreviewed; 226 AA.
AC W2TX99;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Laminin G domain protein {ECO:0000313|EMBL:ETN85657.1};
GN ORFNames=NECAME_06276 {ECO:0000313|EMBL:ETN85657.1};
OS Necator americanus (Human hookworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae; Bunostominae;
OC Necator.
OX NCBI_TaxID=51031 {ECO:0000313|EMBL:ETN85657.1, ECO:0000313|Proteomes:UP000053676};
RN [1] {ECO:0000313|Proteomes:UP000053676}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24441737; DOI=10.1038/ng.2875;
RA Tang Y.T., Gao X., Rosa B.A., Abubucker S., Hallsworth-Pepin K., Martin J.,
RA Tyagi R., Heizer E., Zhang X., Bhonagiri-Palsikar V., Minx P., Warren W.C.,
RA Wang Q., Zhan B., Hotez P.J., Sternberg P.W., Dougall A., Gaze S.T.,
RA Mulvenna J., Sotillo J., Ranganathan S., Rabelo E.M., Wilson R.K.,
RA Felgner P.L., Bethony J., Hawdon J.M., Gasser R.B., Loukas A., Mitreva M.;
RT "Genome of the human hookworm Necator americanus.";
RL Nat. Genet. 46:261-269(2014).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR EMBL; KI657690; ETN85657.1; -; Genomic_DNA.
DR RefSeq; XP_013307884.1; XM_013452430.1.
DR AlphaFoldDB; W2TX99; -.
DR STRING; 51031.W2TX99; -.
DR EnsemblMetazoa; NECAME_06276; NECAME_06276; NECAME_06276.
DR GeneID; 25346308; -.
DR KEGG; nai:NECAME_06276; -.
DR CTD; 25346308; -.
DR OrthoDB; 2999458at2759; -.
DR Proteomes; UP000053676; Unassembled WGS sequence.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF67; LAMININ SUBUNIT ALPHA-LIKE PROTEIN; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 1.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053676}.
FT DOMAIN 92..226
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 183..226
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 187..220
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 226 AA; 24733 MW; DC9FA9FC68E502BB CRC64;
MTTRRPKIIK PYKPSVNITT PTPTVVTTVP VVTKASNVTE TPTEVLTTTP EVVKEHVVET
TMTAEPNRSA PVPDGACALR LDPIQYKDEV DGNRFGLQPN SRLEYEIVPD SFDKSGTFSL
QLRPTASNGV IFFATNDKHT DHIGLFLLNG RVVLSFDTGA GQTVIRSNRS ILTGEWHSVK
ASRRGNEGSL VVDDESAEAI EGLHSSKDRK QEHSQKKPKE ANVVAD
//
