ID   W2ZD44_PHYPR            Unreviewed;       462 AA.
AC   W2ZD44;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Prefoldin, alpha subunit {ECO:0000313|EMBL:ETP45020.1};
GN   ORFNames=F442_08486 {ECO:0000313|EMBL:ETP45020.1};
OS   Phytophthora parasitica P10297.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP45020.1, ECO:0000313|Proteomes:UP000018948};
RN   [1] {ECO:0000313|EMBL:ETP45020.1, ECO:0000313|Proteomes:UP000018948}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P10297 {ECO:0000313|EMBL:ETP45020.1,
RC   ECO:0000313|Proteomes:UP000018948};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA   Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA   Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA   Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA   Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA   Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA   Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P10297.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the RNA polymerase II subunit 5-mediating
CC       protein family. {ECO:0000256|ARBA:ARBA00038295}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP45020.1}.
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DR   EMBL; ANIY01001769; ETP45020.1; -; Genomic_DNA.
DR   AlphaFoldDB; W2ZD44; -.
DR   EnsemblProtists; ETP45020; ETP45020; F442_08486.
DR   Proteomes; UP000018948; Unassembled WGS sequence.
DR   CDD; cd00584; Prefoldin_alpha; 1.
DR   Gene3D; 1.10.287.370; -; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   InterPro; IPR009053; Prefoldin.
DR   InterPro; IPR004127; Prefoldin_subunit_alpha.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR013105; TPR_2.
DR   InterPro; IPR019734; TPR_repeat.
DR   NCBIfam; TIGR00293; prefoldin subunit alpha; 1.
DR   PANTHER; PTHR15111; RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3; 1.
DR   PANTHER; PTHR15111:SF0; UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1; 1.
DR   Pfam; PF02996; Prefoldin; 1.
DR   Pfam; PF00515; TPR_1; 1.
DR   Pfam; PF07719; TPR_2; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF46579; Prefoldin; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50005; TPR; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW   TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW   ProRule:PRU00339}.
FT   REPEAT          218..251
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REPEAT          286..319
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT   REGION          330..383
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          403..427
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          13..40
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          93..120
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        357..371
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   462 AA;  51236 MW;  21A9800435D291A7 CRC64;
     MAALGVMAEA ANARLLQERI ESVREQVTQL QDQVDRFDAV ADTLTELPKK LSHKVMVPLG
     KRAMVPGKIV RSNEVLAHLG DEYFSWRSTP QALEIIERKK KALRKQIEMQ EENLRELSAK
     QTDVGSVAQL QKMYEDENIR EIQETEEESE LGPIPRATDE DIKEYFEVEE EERLKQEQAA
     WNWDDMMKRM EDLEAREAAG EGLEDKTTKE EESAEAQAAA LKAKGNDAFA RRRFQAAIQY
     YSQAIELDPT SHILYGNRAA AYHRLKKYKQ ALDDSDVAVS LHEPWVKGHY RRACALAALE
     QFEDAAEAYE RAMELCPTDE KLGEKAKQMR EKAKAKANGD NVAAQVAESK PQSAPAPSTV
     EPVPVTSPSL KPPVPASSST SFVSASSAST AFSGSIVEHE ITEKTSTPVS APVASPFSGP
     RQSRFQGTNY TGQTVTLEPV GEAQPVKRVS RFKAARAARG SN
//