ID W2ZEK2_PHYPR Unreviewed; 2473 AA.
AC W2ZEK2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=EF-hand domain-containing protein {ECO:0000259|PROSITE:PS50222};
GN ORFNames=F442_08803 {ECO:0000313|EMBL:ETP44619.1};
OS Phytophthora parasitica P10297.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP44619.1, ECO:0000313|Proteomes:UP000018948};
RN [1] {ECO:0000313|EMBL:ETP44619.1, ECO:0000313|Proteomes:UP000018948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P10297 {ECO:0000313|EMBL:ETP44619.1,
RC ECO:0000313|Proteomes:UP000018948};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P10297.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP44619.1}.
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DR EMBL; ANIY01001845; ETP44619.1; -; Genomic_DNA.
DR EnsemblProtists; ETP44619; ETP44619; F442_08803.
DR Proteomes; UP000018948; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0019900; F:kinase binding; IEA:InterPro.
DR GO; GO:0019722; P:calcium-mediated signaling; IEA:InterPro.
DR CDD; cd00051; EFh; 16.
DR Gene3D; 1.10.238.10; EF-hand; 11.
DR InterPro; IPR045198; CNBL1-10.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR23056; CALCINEURIN B; 1.
DR PANTHER; PTHR23056:SF143; CALCINEURIN B-LIKE PROTEIN 8; 1.
DR Pfam; PF13202; EF-hand_5; 6.
DR Pfam; PF13499; EF-hand_7; 11.
DR SMART; SM00054; EFh; 32.
DR SUPFAM; SSF47473; EF-hand; 11.
DR PROSITE; PS00018; EF_HAND_1; 30.
DR PROSITE; PS50222; EF_HAND_2; 31.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 241..276
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 413..448
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 449..484
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 510..538
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 627..662
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 663..698
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 718..753
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 842..877
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 878..913
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 932..967
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1063..1098
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1100..1135
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1154..1189
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1257..1292
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1293..1328
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1347..1382
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1465..1500
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1501..1536
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1554..1589
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1659..1694
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1695..1730
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1750..1785
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1856..1891
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1892..1927
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1946..1981
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2064..2099
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2100..2135
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2154..2189
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2350..2385
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2386..2421
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 2440..2473
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REGION 89..155
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 966..997
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2200..2257
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 95..111
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..155
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2200..2236
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2473 AA; 275900 MW; 43D8497498B8FDCF CRC64;
MTQDAARVSA VTLLLGNEAR ELLLCPGLPL QELLQCITAG FPGVNKPPVA VRHDSSHVYY
PLSLLCRSPE LFENASFHLV LDGEPLEAQE PIRKSNRHRH RAHGRKRGAK AHDMPNRREY
QAVTTTSEAN EEDEDVDDSE GEEKEDFEAA STEDELDLDL SDFELPQLVN VFTQACPTGA
LDRITFNRCL EKILSQSGRY DPQARKMFTR LFNIFEEQST RKDIVDVADF LGGVSVFACG
ERDEKIQLTF ELYDMDGDGF ISKEEMMKYL TAVFLVIGES TPELFQQNNI NPAELGIVTA
SQCFAESTLN RDGKLSYEAF REWYSKPGPT QLVASKRGKT KTGGNGVQAS EGLDLATLRE
LTGLSALSAS DLFSIFSASS SNNGGKKEVL TRTEFKRCFY AILERLNREP THEIAKFLDR
LFDAFDEDES DCVDFVELSS GLSVLCGDSN EDKVMAAFSL FDTDGDGYIT QQEMETYLAS
VFKVMYETTP ATRQFIGIDA KTLAHYTTLQ AFEEADVNRD GKLSLEEFRS WYWVYGRHYQ
QHTMGPPAGP HRQPGMTDHH AFGTSNFVAS LTGLRDRAPS DVFEVIAAKV NEDGVLSREA
FFSIVDELVE DQAASTKHKP GVEEKNQLQK IMETVFDGFD TDHDGFVDFC ELSSGISVLC
SGSQEEKIKS TFTLFDINQD GFISRDEMET YLASVYRIVF MTSPTTMQQL HGISPEELAR
ITTADAFTLA DTNQDDRLSF EEFTKWYSTQ GAPQLPMMQP AGAPTFSNGA VSSPRVSSMF
SRGVLAEMKE LTNLSAYDVN DIFEFFQASA DKEGNVSQPV FFRCFNKLLA KDGRTSRETQ
MKTQQLLKEL FELFDADKNG VVDVQELGAG LSILCGGSRA DKAKSMFTLY DVNHDGYISP
EEMTSYLTSV FKVMFKASPE LPAKTGMTPE QLAKTTTREC FRAFDHNRDG QLSFDEFRVW
FEQQNPHTQR PQVSNGNSGS RPSAPATTSS SGSSDADASG VIPIEVAKKL SGLEGMSLDE
VSEIFSAATG GGKRISRRIF DECFYKHICS KATLGLSVED STRVHEVINR LFTAFDSEQK
GIVDFNELIS GLSILCGASS RDEKVLVAFK VYDTNGDGVI SEEEMTHYLG SVFKLLYALD
PTRKQQLEIS AKTLAAVTAS EIFEVADVNK DGNLTFEEFQ KWYSRPEQSS FNEIVAPLDL
NEVRQLTNLG NLDVVEVFER FAEHADEDGM LNRESFDKCF FEIIEMAHPR TQIEKLRAKM
VADRLYDVFD RDGNGQIDFS ELASGLSVLC KGARDAKVRA AFRLYDFNED GFISLDEMKR
YLTSIFKVLY EVQPEMRQET GVSAEELGVV TAEQAFLEAD SNHDGKLSYD EFLTWYNSPA
QAGISSAVAK NAIVDSSLHW MPLNEIKQLT NLAQYEPEEV FEIFAGEADE DGLLSRDAFN
ESFRKVISGQ KSKGTQASDV ETQKKLQEVV DGLFDLFDTD NSGAVDFGEL ASGLSVLCGG
TKDQKVEAAF SLFDFNGDGF ISLDEMTRYL TSVFRVLFQV SPDTQSLGVT PEELGEVTAQ
QAFAEADQDH DGQLTLKEFQ QWYQQPGGIG EVAKNGEQLF SLAEARRLTN LQAFSPMEVF
EALAECADEQ GYVPRESFDK CFRKIISTNQ GIKSDEYQRI NTILNRLFEL FDVDKNGMVD
FSEISSGLSV FCGGSSEEKI RAAFALYDYN ADGYISMEEM TRYLTSVFRV LKEASPSGLQ
QLGRESPEEL GVRTAQQAFA EADLDHDGRL SFPEFRKWYT RSNAANMERL IQNNIPEWLS
LREVRRLTNL ESFSAQQVLN TFAKFTAADG TMDKETFRQA FDHFKVESAT QESRDRLQLL
VDRIFELFDK DSNGLVDFNE LASGLSVLCG GSQADKVRAA FNLYDVNHDG YISLGEMRLY
LTSVFKVLFE VNPDSEARMG VTPEELGEIT AEQAFVEADH DRDGKLSFEE FSQWYMQPKR
VGDLPVPAVL GEQQQERKHQ VPDWVSLDVV KQMTNLEKYT ADEVFEIFAN RCSENGTLSR
EAFEECFEQL VDEQYKNDEV SLARLRLILN RLFIIFDENQ DGTVDFCELT SGLSVLCGGS
REEKVRAAFS LYDLNQDGFI SLDEMVRYLA SVFKVLYETS PGTDRKLGVR PEELATITAE
QCFLEADLNE DGKLSFDEFV AWYSKSSRFE APAAGVSSIL GQQQATKGNT SESQSNGSFS
RDNSKVGSQS GSPAPESPRK TVWGAGKGPG PSGVSTAPVS FPSDKIYGMT GSNGDALLSP
NSASALNMNS SNMEHVRQLL KLDTYEVNDV LEIFAEAAPS GELTFAAFKK CFDQIIRLAG
GHESTEERQE ADAMIRRLFC VFDTDNSNTV DFGELASGLS VLSGSSMDDK VRAAFQLYDI
NGDGYITQEE MISYMTSIFK VMYETTDSTK TKMGVSPEEL ARVTAEQCFK EADLNGDNKL
SFEEFKKWCT SGL
//
