ID W2ZK07_PHYPR Unreviewed; 2759 AA.
AC W2ZK07;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 29.
DE RecName: Full=TOG domain-containing protein {ECO:0000259|SMART:SM01349};
GN ORFNames=F442_06468 {ECO:0000313|EMBL:ETP47623.1};
OS Phytophthora parasitica P10297.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317064 {ECO:0000313|EMBL:ETP47623.1, ECO:0000313|Proteomes:UP000018948};
RN [1] {ECO:0000313|EMBL:ETP47623.1, ECO:0000313|Proteomes:UP000018948}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P10297 {ECO:0000313|EMBL:ETP47623.1,
RC ECO:0000313|Proteomes:UP000018948};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Walker B., Young S.K., Zeng Q., Gargeya S.,
RA Fitzgerald M., Haas B., Abouelleil A., Allen A.W., Alvarado L.,
RA Arachchi H.M., Berlin A.M., Chapman S.B., Gainer-Dewar J., Goldberg J.,
RA Griggs A., Gujja S., Hansen M., Howarth C., Imamovic A., Ireland A.,
RA Larimer J., McCowan C., Murphy C., Pearson M., Poon T.W., Priest M.,
RA Roberts A., Saif S., Shea T., Sisk P., Sykes S., Wortman J., Nusbaum C.,
RA Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P10297.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GCN1 family.
CC {ECO:0000256|ARBA:ARBA00007366}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP47623.1}.
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DR EMBL; ANIY01001372; ETP47623.1; -; Genomic_DNA.
DR EnsemblProtists; ETP47623; ETP47623; F442_06468.
DR Proteomes; UP000018948; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 6.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR InterPro; IPR034085; TOG.
DR PANTHER; PTHR23346:SF7; EIF-2-ALPHA KINASE ACTIVATOR GCN1; 1.
DR PANTHER; PTHR23346; TRANSLATIONAL ACTIVATOR GCN1-RELATED; 1.
DR Pfam; PF02985; HEAT; 1.
DR Pfam; PF13513; HEAT_EZ; 1.
DR SMART; SM01349; TOG; 1.
DR SUPFAM; SSF48371; ARM repeat; 5.
DR PROSITE; PS50077; HEAT_REPEAT; 4.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018948};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1434..1666
FT /note="TOG"
FT /evidence="ECO:0000259|SMART:SM01349"
FT REPEAT 1528..1564
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1607..1644
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 1727..1765
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 2078..2116
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 790..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 793..827
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2759 AA; 299739 MW; 4616F70A300146CC CRC64;
MAEQEDVLRS LLDAAVLRPS HLVFIQSYQH EVVTKCKASE LPLKRLASQI LAETYRCQYR
SSEQHLRALL AEACKELPKF PEIFSHVLRA KAPALVASFA SARVIALRLS CVVLDAALIA
DSKPDAAWLN ELLAAQSCLL EATIGDSERS QKQARKAPLK LLKKHGQTLL QSYVDVITSA
EPEEQHYQLW FVLSLSDLLN KETQELMWNK YVVWAFESKK RTFAPLEKSD ARFKNLSYGQ
FEEIIMPPMA KMLKKAPDTV IEAVGAFVHA TPLDFGRYVS DFFQSVLISK LRAPKDDVRA
LAVALAGALT RSFRQSEHMK EFVAVMATLL DGKHGILAQF YQREVAFAVL NDAADAAMVQ
LDASEVQEIA SVAIASLLKA VGKEAHEQTR HLGLLTLGKW LALAGTDELD VATVTALKTG
FKNKPEPVVA GYLRALAVLC RSRATAVVPF ADEVVAVIKD SNKKPNVAHL DGVLAVAVAG
VIASASSEMD ACMAQEGVAD LLLSSTSFVG HSVRSLLSTV TSTSRQAAAL ESPEISALAA
LSRALVWVLA SQQSDVSEAY SLLVELLCSS SLTVRQSAER AVETMYQSSL EHCAGLVAAF
EKKIDALSGQ EEASLPPAGV LRRALRVLVP AAISKADDTK VQVFPWVLFL AHNPFLVAGK
KAEAFSREWQ SIRRRFLSPS TDTAKSEDDD DDEPPSDASL VDNFIEEHEE VKTAVVELLA
NASTGKLYSA SALQRLAAQR ALATLLDFAG NGEGEDLALH DIIEDLLAKR LDDEQIDALS
EEDVAICQTP FDELYEPKKE GEEGETTSRN KRGGRRGNED DQWEQELREE LERKKRAEEG
AQKKVYTPEQ KAQLEQQQEV RRKVQETHRV VSAVFEAIDM LALTRPDELH PALPYLLRSA
RVLFTCPLFE SEASNALMAL AKAINPELLR SSYQDVASAL RIALELDQLT SDKDKAAHIA
EVEGLFLRLL AELMEYVFGF QFETEADFDA DAPCNLIPPP TLHLLFPVLR DLLRFAPDLR
RWSLPLFAVH ARMIPDEEEE EVGDVAAQRL LRRDMLQLTL LLLSQQATGS ALPISNPDLA
PGKLLTSLCL GPELTAAEWA PLLGDDGLLS EEASARGEVL TALLNVVQSD EGGEEFRNAK
PSSLLISRLY CCRFDSDEKN RTLANQIWDA TGAAVTALYA GPLLVLLNHT HASARESASL
ALADGMRQFP KSVTPLLNNL KTQFLSSQPK PIERKDEFGI PTVRRPGAQA AELDEDVRTM
CPRLGVALCL EKAAEVAGPE AMSSANTMAL LTFVMEHGLG DPNSKVRAQM RKTGVQAVAS
LGGGVNTAPL LEMFERFLET TAPPAAPAVK TSGGKKAKVG THLAAQEEEM LQQSKQALSI
YDHQREGVVV CLGSLAKHMA PTDPKVSSIV DSLIEALDIP SESVQRSVAM CLSPLMSAVK
DRTTGILDDL LKRVTEGETF GERMGAAYGV SAVVKGLGIS ALKIHNIIPR LEESMKTGGA
NARQGAMLVF ECLSQRLGLL FEPYIIVILP VMLKCSADAS PQVREAASHT AKGIMSNLSA
HGVKLVLPSL LGALEESAWR TKQSGIQILG SMAYCAPRQL GSCLPQVVPK LMAALTDSHP
KVREAGKSAL RDVGSVVRNP EIATISKVLL DALEDPNRHT AEALQQLQST SFQHSIDAPS
LALVMPIITR GLKDRAGDAK KKAALIVGSM CSMINDAKDL VPYMETVLPS LKTQLIDPIP
EVRAVAAKAL GKLVKGLGER HFADMLTWLL EAMKDDEVGP VERSGAAQGL CEVVVALGIE
RVERVMREDI LPLARHPKYS VREGVLWVMA FLPPALGKQF SMFLREALPI VVAGLSDEAE
SVRDVAMHSG HVVVNAHALS HTRDLLPSLE AGLFDDSWRI RQSSVMLLGD LMYRISGTRV
VAVVSGDNDD DEETSGSAAG DRAIIKLLGI QRRNAILASL YMIRSDTSAV VRQSALQVWK
SVVANTPKTL RQILEALMNA IVSALSGDNM EKQTMAGRTL GEIVRKLGEH VLPEVVPILR
AGLSPSLPTG RRQGACIGLA EVIDCCTKKQ IEDYVDTLVD AVLDGVCDEL PEVRASAAQA
FDVLHKGIGY RAIDETVPMV LERIHSSPSA EEQERALLGL QEILRVKSRE VLPYLIPRLL
VMPVTASAAR AVSRVAQATG AVIHFQVEKI FATFFAQYVE LLEDDSSDAS KTELSEEIKR
SLRDVVLGVE APGIHWLAIE LCKYCESENV LDRALAFELV GEFCSHATVP YDDQAPLYLK
QIVLHLNDQN DAVVRAASAA LKGMNATIKP EQFAQHLDFI RQSINSMVSD ARHRKGGVGD
GEYLLPGLCI PKGLEPFLPS YQWALMNGSP ELRQSAAAGL GELVELSSAP ALRPYLIKLT
GPLIRIAGDR FPGHVKAAIL QTLEIILTKG GVALKPFLPQ LQTTFVKALN DTAVDVRARG
ASALSLLVTL SPRVEPLLAE LTERLRTTTG GVREANLEAV ASVVERVGDK LSAAGRSTLE
CALEEMLESS EDALRDGASK CLASCVASTA NNGDLETAQK QLLDYSLANI SADDLQAQPW
QRRQSAAVFT ALVLHKHPAL LSAEVAAPLT TTLVALALDE QTAVRNNALN AIGALVKRQA
HVEDVAALVP VLVEGVTHKN KDVIRGALRV VKLTAKRSPE QTREHLTALV PAVFQLIKSN
NMAVKLPAER TLLYLLEVHS RPETQAEYLR SGAADAKIIG EYTRRVLSKL KADSGDESD
//
