ID   W3AKS4_9FIRM            Unreviewed;       563 AA.
AC   W3AKS4;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=Na/Pi-cotransporter {ECO:0000313|EMBL:ETP71209.1};
GN   ORFNames=UYO_2847 {ECO:0000313|EMBL:ETP71209.1};
OS   Lachnospiraceae bacterium JC7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP71209.1, ECO:0000313|Proteomes:UP000018967};
RN   [1] {ECO:0000313|EMBL:ETP71209.1, ECO:0000313|Proteomes:UP000018967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JC7 {ECO:0000313|EMBL:ETP71209.1,
RC   ECO:0000313|Proteomes:UP000018967};
RA   Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA   O Cuiv P., Morrison M.;
RT   "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT   identified member of the bovine rumen core microbiota.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP71209.1}.
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DR   EMBL; ALYD01000063; ETP71209.1; -; Genomic_DNA.
DR   AlphaFoldDB; W3AKS4; -.
DR   PATRIC; fig|1165092.3.peg.2785; -.
DR   OrthoDB; 9763003at2; -.
DR   Proteomes; UP000018967; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005436; F:sodium:phosphate symporter activity; IEA:InterPro.
DR   GO; GO:0044341; P:sodium-dependent phosphate transport; IEA:InterPro.
DR   InterPro; IPR003841; Na/Pi_transpt.
DR   InterPro; IPR004633; NaPi_cotrn-rel/YqeW-like.
DR   InterPro; IPR038078; PhoU-like_sf.
DR   InterPro; IPR026022; PhoU_dom.
DR   NCBIfam; NF037997; Na_Pi_symport; 1.
DR   NCBIfam; TIGR00704; NaPi_cotrn_rel; 1.
DR   PANTHER; PTHR10010:SF46; SODIUM_PHOSPHATE COTRANSPORTER-RELATED; 1.
DR   PANTHER; PTHR10010; SOLUTE CARRIER FAMILY 34 SODIUM PHOSPHATE , MEMBER 2-RELATED; 1.
DR   Pfam; PF02690; Na_Pi_cotrans; 2.
DR   Pfam; PF01895; PhoU; 2.
DR   SUPFAM; SSF109755; PhoU-like; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        6..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        83..105
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        117..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..171
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        183..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        255..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        299..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          371..455
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
FT   DOMAIN          475..558
FT                   /note="PhoU"
FT                   /evidence="ECO:0000259|Pfam:PF01895"
SQ   SEQUENCE   563 AA;  60555 MW;  01DCDEE3F7BC0E46 CRC64;
     MTVEHLSSMF SLFGGLGMFL YGMTVMSDGM QKAAGSRMSR FLDMVTGNRI MAVILGAGIT
     ALIQSSSATT VMVVGFVNAG IMNLSQAVGI IMGANIGTTI TAWMVSLTQI SSDMLTVLKP
     DFFAPVLVGF GAFRILFGKK GTDDLLGDFC IGVGFIFIGL GFMSGAVAPY ADSPIFSKAF
     RTIGGNPVLG ILVGAVVTGI IQSSAASVSI LQTLALAGAV PRASGFYITL GQNIGTCITA
     MISSTGTTRT ARRAAVIHLL FNVSGAILFG AVIFIGTFFV PDFMTGKLTP VEISVFHTIF
     NTLCTLVLFP LGDFLVNLSG AIVPEEKKEE SDETVEDKLN QEAQRLRRHL DERMLESPAI
     ALAAAKSEVV NLGRVVAVNI NAACNAITDD GENMIQNVYD REKIIDHMTN LLTDYLIKID
     KLSLSDKQKL QVTIMLNALT DIERAGDHAE NIAEKAKYAH DKKTEFTDYG LADLDRISSK
     AQESFSLSLN AFEDGSIDEM VDTAKAEDQV DAMEREMRQN HMMRLSMGEC TTDAGVVFLD
     IIGDLERISD HADNIAGYVK QLI
//