ID W3AN14_9FIRM Unreviewed; 412 AA.
AC W3AN14;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Alanyl-tRNA synthetase {ECO:0000313|EMBL:ETP72415.1};
GN ORFNames=UYO_1626 {ECO:0000313|EMBL:ETP72415.1};
OS Lachnospiraceae bacterium JC7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP72415.1, ECO:0000313|Proteomes:UP000018967};
RN [1] {ECO:0000313|EMBL:ETP72415.1, ECO:0000313|Proteomes:UP000018967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JC7 {ECO:0000313|EMBL:ETP72415.1,
RC ECO:0000313|Proteomes:UP000018967};
RA Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA O Cuiv P., Morrison M.;
RT "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT identified member of the bovine rumen core microbiota.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP72415.1}.
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DR EMBL; ALYD01000015; ETP72415.1; -; Genomic_DNA.
DR AlphaFoldDB; W3AN14; -.
DR PATRIC; fig|1165092.3.peg.1613; -.
DR OrthoDB; 9812949at2; -.
DR Proteomes; UP000018967; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004813; F:alanine-tRNA ligase activity; IEA:UniProtKB-EC.
DR GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro.
DR Gene3D; 2.40.30.130; -; 1.
DR InterPro; IPR018165; Ala-tRNA-synth_IIc_core.
DR InterPro; IPR018163; Thr/Ala-tRNA-synth_IIc_edit.
DR InterPro; IPR009000; Transl_B-barrel_sf.
DR InterPro; IPR012947; tRNA_SAD.
DR PANTHER; PTHR43462; ALANYL-TRNA EDITING PROTEIN; 1.
DR PANTHER; PTHR43462:SF1; ALANYL-TRNA EDITING PROTEIN AARSD1; 1.
DR Pfam; PF07973; tRNA_SAD; 1.
DR SMART; SM00863; tRNA_SAD; 1.
DR SUPFAM; SSF55186; ThrRS/AlaRS common domain; 1.
DR SUPFAM; SSF50447; Translation proteins; 1.
DR PROSITE; PS50860; AA_TRNA_LIGASE_II_ALA; 1.
PE 4: Predicted;
KW Aminoacyl-tRNA synthetase {ECO:0000313|EMBL:ETP72415.1};
KW Ligase {ECO:0000313|EMBL:ETP72415.1}.
FT DOMAIN 1..253
FT /note="Alanyl-transfer RNA synthetases family profile"
FT /evidence="ECO:0000259|PROSITE:PS50860"
SQ SEQUENCE 412 AA; 46306 MW; FDC08FF5C14EF1F1 CRC64;
MEKNALYYQF PYVKEFDATV TSCEERDGQY QVELDAHGFY PEGGGQAADH GMIGDALVSD
VQEESLKDPE TGEKLTDEKG NVMVRILHTV ARALEVGRSY HCSIDWERRM RNSRNHSGEH
IVSGLVHKHY GYNNVGFHMS DVMTIDFDGV LTWEQLMKIE EEANEVVLAN RAVDQIWPSE
EELQDTDFRS KKALKGDVRL VDLGGADLCA CCGTHVMTTG EIGLIKILSV LGHKGGVRVE
LFCGKDALQD YRNKHNDLLE LSHMLSFAPS EVKEAVRQHM EQSAAKDRRI AELNQRYYAM
KAETLKDFTG VLVDVEDGMN NVELRKCCDY FMKHTKAKVV GVFGLKDVDG SKRDVDSSWN
YVIGSETEDV RCRAKDFNAL INGRGGGQKE MIQGSAESTE DKIRKAMQDI FG
//
