ID W3ART5_9FIRM Unreviewed; 200 AA.
AC W3ART5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=5'-deoxynucleotidase {ECO:0000256|ARBA:ARBA00012964};
DE EC=3.1.3.89 {ECO:0000256|ARBA:ARBA00012964};
GN ORFNames=UYO_1204 {ECO:0000313|EMBL:ETP72787.1};
OS Lachnospiraceae bacterium JC7.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP72787.1, ECO:0000313|Proteomes:UP000018967};
RN [1] {ECO:0000313|EMBL:ETP72787.1, ECO:0000313|Proteomes:UP000018967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JC7 {ECO:0000313|EMBL:ETP72787.1,
RC ECO:0000313|Proteomes:UP000018967};
RA Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA O Cuiv P., Morrison M.;
RT "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT identified member of the bovine rumen core microbiota.";
RL Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-phosphate + H2O = a 2'-
CC deoxyribonucleoside + phosphate; Xref=Rhea:RHEA:36167,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:18274, ChEBI:CHEBI:43474,
CC ChEBI:CHEBI:65317; EC=3.1.3.89;
CC Evidence={ECO:0000256|ARBA:ARBA00001638};
CC -!- COFACTOR:
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC Evidence={ECO:0000256|ARBA:ARBA00001941};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETP72787.1}.
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DR EMBL; ALYD01000010; ETP72787.1; -; Genomic_DNA.
DR AlphaFoldDB; W3ART5; -.
DR PATRIC; fig|1165092.3.peg.1201; -.
DR OrthoDB; 9812744at2; -.
DR Proteomes; UP000018967; Unassembled WGS sequence.
DR GO; GO:0002953; F:5'-deoxynucleotidase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR039356; YfbR/HDDC2.
DR PANTHER; PTHR11845:SF13; 5'-DEOXYNUCLEOTIDASE HDDC2; 1.
DR PANTHER; PTHR11845; UNCHARACTERIZED; 1.
DR Pfam; PF12917; YfbR-like; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
DR PROSITE; PS51831; HD; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:ETP72787.1}.
FT DOMAIN 30..145
FT /note="HD"
FT /evidence="ECO:0000259|PROSITE:PS51831"
SQ SEQUENCE 200 AA; 22867 MW; A47F128B01AA23BC CRC64;
MDRFTFFATI SRMKYIERWA LMRNSRPENL SEHAVEVAMI AHALCIIGNV RYGRKLDGEK
AALIGIYHDA SEIITGDMPT PVKYFNKEIT GAYKSLEHIA EKSLLERLPD DLRPAFDEIF
NGDRTDENEK YMRKLVKAAD KISALIKCIE EENSGNREFC TAKVSTLKSL EAMKENYPEV
NDFLQEFLPS YGSTLDELAL
//
