ID   W3ASV0_9FIRM            Unreviewed;       340 AA.
AC   W3ASV0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   SubName: Full=Uroporphyrinogen decarboxylase (URO-D) {ECO:0000313|EMBL:ETP73137.1};
GN   ORFNames=UYO_0816 {ECO:0000313|EMBL:ETP73137.1};
OS   Lachnospiraceae bacterium JC7.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae.
OX   NCBI_TaxID=1165092 {ECO:0000313|EMBL:ETP73137.1, ECO:0000313|Proteomes:UP000018967};
RN   [1] {ECO:0000313|EMBL:ETP73137.1, ECO:0000313|Proteomes:UP000018967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JC7 {ECO:0000313|EMBL:ETP73137.1,
RC   ECO:0000313|Proteomes:UP000018967};
RA   Rosewarne C.P., Cheung J.L., Evans P.N., Tomkins N.W., Denman S.E.,
RA   O Cuiv P., Morrison M.;
RT   "Isolation and genomic characterisation of Lachnospiraceae sp. JC7, a newly
RT   identified member of the bovine rumen core microbiota.";
RL   Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETP73137.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; ALYD01000006; ETP73137.1; -; Genomic_DNA.
DR   AlphaFoldDB; W3ASV0; -.
DR   PATRIC; fig|1165092.3.peg.821; -.
DR   OrthoDB; 7375127at2; -.
DR   Proteomes; UP000018967; Unassembled WGS sequence.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:InterPro.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
FT   DOMAIN          75..333
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
SQ   SEQUENCE   340 AA;  39575 MW;  29819B171BD446E4 CRC64;
     MAENKRDLLK QALDNHETYR IPMGFWHHFI LGEEQFKGLQ NKDILERAIE GHKKYFETTD
     PDMMKLMNEG FMGYPPVMDN RLETGEDLLK IRSLGENHPW ITEQVAHVRR LVDLFGDKVM
     TFYNIFAPVQ VIRIRLEFYD LDFERFVYLA DNFPDELHAA GMEIQKDLKI LVRKLLTETK
     LDGIYYCVQN IQSRKYDRAM YDRLIRPTET EVLETANQYS DYNILHICGY AHHKNDLGFY
     RDYESKAYNW AVFTEGVSLQ EGKKLFGGKC VLGGFDNNPG TLIDSGTREE IEAFVQKLIR
     ENGFKGYILG ADCSIPNDIN DGRIHWISRA VKKENTTGGQ
//