ID   W3WP46_PESFW            Unreviewed;      1575 AA.
AC   W3WP46;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   24-JAN-2024, entry version 36.
DE   RecName: Full=NACHT domain-containing protein {ECO:0000259|PROSITE:PS50837};
GN   ORFNames=PFICI_12518 {ECO:0000313|EMBL:ETS75574.1};
OS   Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX   NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS75574.1, ECO:0000313|Proteomes:UP000030651};
RN   [1] {ECO:0000313|Proteomes:UP000030651}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX   PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA   Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA   Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT   "Genomic and transcriptomic analysis of the endophytic fungus
RT   Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT   of natural products.";
RL   BMC Genomics 16:28-28(2015).
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DR   EMBL; KI912118; ETS75574.1; -; Genomic_DNA.
DR   RefSeq; XP_007839290.1; XM_007841099.1.
DR   GeneID; 19277531; -.
DR   KEGG; pfy:PFICI_12518; -.
DR   eggNOG; KOG2029; Eukaryota.
DR   HOGENOM; CLU_003175_1_0_1; -.
DR   InParanoid; W3WP46; -.
DR   OrthoDB; 2251579at2759; -.
DR   Proteomes; UP000030651; Unassembled WGS sequence.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46844; SLR5058 PROTEIN; 1.
DR   PANTHER; PTHR46844:SF1; SLR5058 PROTEIN; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR   SUPFAM; SSF48371; ARM repeat; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          438..565
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
FT   REGION          385..408
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1575 AA;  180878 MW;  D2D95E9DA936F517 CRC64;
     MDTYVVVFTI IILFLVQNFL NRFRYVSATP SSVPTDDPTT TSSRPRPVRL DQINPLINKD
     TNIDLDVIAI HGFDARSPDT WTYKSTANEP GVNWLENPEM LPGVVGSARI FTCDWPSDFF
     ESSDFVQKTF DKFAEGLLDG IESRPPAKGC TQAEGPPILF IASCLGGVML MKALVEEGMK
     CNDSPTLKAT RGIVFLATPF RGTAFADVAH WAEPSLRIWA SLRAQAVSNL LGQIKEGSEL
     TKLVGDFTRL CQRDGPFMAT FFENEKSRLL RRVGSFRFSI FKEKKLLVPE SSATLDIVRN
     RKPLNRTHGK MNNFRGPGDD DYKIVAESIK EMAKSIREGR LLHRAYEYIN KRHYNDNRLK
     IVRISDDELS MSECYVNLAI TYQPSRNNGS ESKDPTSSSQ SSLFRRLNVE SPNKNSEVEL
     LKLFDRRKDH AGREVGPRKI LIRGQAGVGK TTLCKKMVYE FSRNEMWNNT FDRILWIPLR
     NLKLLEHHNL EALFLREFFS RETLDKGRMF ATELHSQVSN GKDEKTLFIL DGLDEVYDAL
     ERGHWLHDIL EELLTMPASI VTSRPRVSLP GDLSKGFDLE LETIGFYREQ VDSYIEKVFT
     HSKVKGTKWD RVDGLRSVLR QHKLLQQLVR IPIQLDALCF IWDDDHRSLQ SNFKLETMTN
     IYQAIMKILW KKDLLRLGQF GKELTRRDVQ NYPLDKLEIF FQDEVACLEI LAFKGMVDDS
     IVFTESQILA MPTLKPLKAG KLEGLSILRT HELLIPDPTY HFIHLTFQEY FAARYFVRQW
     ISGDTLKRGK HELSSSASNF IKEYKYDDRY NVFWRFVTGL LSLKDHGLEE FFPTLETEPI
     DMIGVVHQRL LMHCWNEVSP DDTKFLAERQ NFEDRLYRAA MEQFKLTDSV SVIEEVEFPE
     KPLLRVLRSF SDELRRTVLR SIMFRGMVPV TALRLIYSSL RDDLDCLERT GLLFSIRLAQ
     STILNDEILG IIKEQISYGN TVQVMAIAVL VDFLMSGDKT SILEKLKQQV TSLESESELV
     RAQFFLAMRS HRRRQEPQTI EFLVSQLQGT LKAHASQDET NLDLQENTSS IFTGWGMYPE
     ASSIITLLGG QPSLPTDVLA IISTQLQNQD AQVRRAAVRS VKAHCPNEFI LKTITPWLDG
     PQLHTREAVL EVLGSWHPLP SEVKKFIIAQ LMHSDAMIRR AVIRPLQKWP NIDAEIFQAV
     GANLTDNDSI TRKEAITLLG AQYLFRDEDI DLFKSILWYD QDLSVRQEAL RVLWSRLDFN
     DIGFDLISEC LQHPGLCSHA LDEWQRRPEL CRNACPEIMQ LLLGSCLKSS NWENRAKTYE
     ILTILHPSDG TYDSLFDVIM NGLKDPVPSV REAVARALNN WSSTEVRYLQ IIIDHLQSVL
     FEKNAGEKYH GYLLRALENF PRPTDDAYLV LSRTLAYPWH HVCSAAVATL QKWPQPRKAV
     IENIVLYLQA SDTKCVSKAL EVLGEWSQLD PDNLRAIAKK LQDKERQLQL AAFNAVVKQQ
     VLNLNVIMPY MESLFRISLR NSHTRRVCWL TEGEKNTVLI GSRALRWQNE QGRVDTWFLL
     EPGIIRRWRE SCTDG
//