ID W3WZA6_PESFW Unreviewed; 1034 AA.
AC W3WZA6;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE RecName: Full=beta-galactosidase {ECO:0000256|ARBA:ARBA00012756};
DE EC=3.2.1.23 {ECO:0000256|ARBA:ARBA00012756};
GN ORFNames=PFICI_10524 {ECO:0000313|EMBL:ETS78462.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS78462.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing beta-D-galactose residues
CC in beta-D-galactosides.; EC=3.2.1.23;
CC Evidence={ECO:0000256|ARBA:ARBA00001412};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 35 family.
CC {ECO:0000256|ARBA:ARBA00009809, ECO:0000256|RuleBase:RU003679}.
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DR EMBL; KI912115; ETS78462.1; -; Genomic_DNA.
DR RefSeq; XP_007837296.1; XM_007839105.1.
DR AlphaFoldDB; W3WZA6; -.
DR GeneID; 19275537; -.
DR KEGG; pfy:PFICI_10524; -.
DR eggNOG; KOG0496; Eukaryota.
DR HOGENOM; CLU_005732_2_0_1; -.
DR InParanoid; W3WZA6; -.
DR OMA; TNNDAIT; -.
DR OrthoDB; 1032627at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.102.20.10; Beta-galactosidase, domain 2; 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR018954; Betagal_dom2.
DR InterPro; IPR037110; Betagal_dom2_sf.
DR InterPro; IPR025972; BetaGal_dom3.
DR InterPro; IPR036833; BetaGal_dom3_sf.
DR InterPro; IPR025300; BetaGal_jelly_roll_dom.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR031330; Gly_Hdrlase_35_cat.
DR InterPro; IPR001944; Glycoside_Hdrlase_35.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR23421:SF122; BETA-GALACTOSIDASE A-RELATED; 1.
DR PANTHER; PTHR23421; BETA-GALACTOSIDASE RELATED; 1.
DR Pfam; PF13364; BetaGal_ABD2; 2.
DR Pfam; PF10435; BetaGal_dom2; 1.
DR Pfam; PF13363; BetaGal_dom3; 1.
DR Pfam; PF01301; Glyco_hydro_35; 1.
DR PRINTS; PR00742; GLHYDRLASE35.
DR SMART; SM01029; BetaGal_dom2; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF117100; Beta-galactosidase LacA, domain 3; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 2.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 436..615
FT /note="Beta-galactosidase"
FT /evidence="ECO:0000259|SMART:SM01029"
SQ SEQUENCE 1034 AA; 114319 MW; AD5C26B852F2BA32 CRC64;
MKGGAAHIRD QSESLPLLQH RKSLPPSKEG KNGGQCLGLS LIISKRLAIW LCTLTLLATF
ALLSRQDHDG AYYTVPQAEQ PKEQPQNIVT WDERSLFIRG QRVMVMSGEL HPWRLVPSLY
DDVFQKIKAL GFNCVSFYVM WALVEPAPGN FTATGVFAYE PFLEAASRAG IYLIARPGPY
INAEVSFGGY PGWMQRVNGQ LRTRNPEYLA ATDNYIAQIG AIIAKAQITN DGPVILYQPE
NEYTWGVPPR FPDGEYMQYV EDQARKAGIV VPIISNDAAP LGHNAPGTGA GEVDIYGHDD
YPLKFDCSNP TSWPKGALNG LYHSIHEVQS PSTPFSILEF QGGAFDPWGG PGFENCALLL
NEEFERVFYK NNLAAGVTIF NIYMVYGGTN WGNIGHPGGY TSYDYGSPIK EDFTVGRKKY
SELKLLAQWL QMSPGYLTAK PGLAEVLTYC NDAAITVTRL KGDSTIGGGS FFIIRHSDYT
STVSTNYKLE LPTSRGKVSI PALYGSLTLN GRDSKIAVTD YDVHGSTLIY STAEILTHQK
YTDRVVLVVY TGPGETNELA IKTTHKPKIL VGDAVAVHHA GDLAIMTWDT SGERKVIRVG
NLFIFATDRD SAYRYWVPSI GKTSAIILGP YLVRNASLHD YRTLSIQADF TENTTVEILG
LSHLKSVIVN GVDTPFRDNN ITISLDIHYK SPQLKIPVLA SLKWRAADSL PELHSSYDDS
QWPSADLSSN NTYQHQWTPT SLFASDYGFH AGVLVFRGHF VAQGTEESFD IQTQGGTAYG
HTVWLNNTFL GSEIGKAGVS NARATYRIPD LLPGKPYVLT VIVDNMGLDE NGVAGVDSGK
APRGILRYNL KSSWFRSTPI DWKLTGNLHG EDSVDRSRGP LNEGGLFAER QGWHLPKPPI
GAFRKRSPLE PISEPGVWIF TSSFDLDLPS DYEIPLSFVL GGVTGGAARI QLYVNGWQYG
KYISHIGPQT RFPVPEGILN YHGENWIALL IWTMEDQTTQ LEDFRLERGL PVYSGRSAVK
LVDSPSWKRR DGAY
//
