ID W3X1E8_PESFW Unreviewed; 579 AA.
AC W3X1E8;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=PFICI_07429 {ECO:0000313|EMBL:ETS79900.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS79900.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KI912113; ETS79900.1; -; Genomic_DNA.
DR RefSeq; XP_007834201.1; XM_007836010.1.
DR AlphaFoldDB; W3X1E8; -.
DR GeneID; 19272442; -.
DR KEGG; pfy:PFICI_07429; -.
DR eggNOG; KOG0254; Eukaryota.
DR HOGENOM; CLU_000960_25_2_1; -.
DR InParanoid; W3X1E8; -.
DR OMA; FGRRWFI; -.
DR OrthoDB; 2663368at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06179; MFS_TRI12_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR010573; MFS_Str1/Tri12-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23501; MAJOR FACILITATOR SUPERFAMILY; 1.
DR PANTHER; PTHR23501:SF109; MAJOR FACILITATOR SUPERFAMILY (MFS) PROFILE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR Pfam; PF06609; TRI12; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..73
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 111..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..187
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 241..260
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 272..291
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 312..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 44..490
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 1..30
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..30
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 62403 MW; 52AAAC3F8B25E72F CRC64;
MEDKQPEIEK SGNQAGSLSD SEKGPKQTNY IPQSDEEYNV TFKTWIVVAI LSFSYGISFW
IIPTLSACVA QVATQLGDVS AQAFFLPIYT LTITIAFMVC GANSDLFGRR WFIIFGNVLL
FIGFILGGRA QNPTQMIAAM AIIGFGAGNA QLAAFAVPEL LPNKWRPVAV TLADAGVVFD
VIVGPIAGRS AIELSYSGWR WLFYVPAILV VISFTGLFFY YYPPAHPRGL PFKQAIRELD
YGGAILFIMS TVLILTGIIY TTTLPSSDPR VLGTLIAGFI LLAIFALYET FMPLKQPLTP
QHVFTKGGGR ELTAPFIAGF VVTMFYYSIN IIYPTMIFVF FTDSTTGWRY AMVLTLPQNL
GFLLGVLLLV TLGSKIGHYR WTYTAAVTLM VVFGTLLALG RPDRFGMMIA FVFLAEVGFG
FAQYLSITFI QFGTKQEELG ISGGLAGVAR FAGGAVALSV YTTILTNTQT AEAARLIPAA
ATGAGLPESS VSQLITALSL GASALAEVPG ITDSIIAAAS TALQQSYVVG LRTTALSSLA
FGIVGIIACA CCQEISHKMN NKIEIFLEND VNAARNTHH
//
