ID W3X8W2_PESFW Unreviewed; 977 AA.
AC W3X8W2;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Importin N-terminal domain-containing protein {ECO:0000259|PROSITE:PS50166};
GN ORFNames=PFICI_04439 {ECO:0000313|EMBL:ETS82563.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS82563.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
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DR EMBL; KI912111; ETS82563.1; -; Genomic_DNA.
DR RefSeq; XP_007831211.1; XM_007833020.1.
DR AlphaFoldDB; W3X8W2; -.
DR STRING; 1229662.W3X8W2; -.
DR GeneID; 19269452; -.
DR KEGG; pfy:PFICI_04439; -.
DR eggNOG; KOG2081; Eukaryota.
DR HOGENOM; CLU_005996_0_0_1; -.
DR InParanoid; W3X8W2; -.
DR OMA; LECITSW; -.
DR OrthoDB; 35663at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006606; P:protein import into nucleus; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR PANTHER; PTHR12363:SF53; MRNA TRANSPORT REGULATOR MTR10; 1.
DR PANTHER; PTHR12363; TRANSPORTIN 3 AND IMPORTIN 13; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 33..100
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 977 AA; 110376 MW; BC9B02FD62F871B2 CRC64;
MASNGAQATF PPEQVLEAML TMRSNDADRK KSAHKFLEEF QKSSSAWTTT FSILQSDAEA
DVKLFAATTL RGKITYDLAT QIPAEQHVAV RTQLLELLKV YAPGPKPIRV QLCVCLAILA
IQMKEWKDVL PLVVSSLGNQ AESHAAILDF LRILPEEVTE GRKITLSEED LNLRTIELLS
DNAPQVVQLL INYAHSSPSA AKNPQLLECI TSWLREVPVT DVVNSPLLDI VFNAVEGDEA
FQEAAECLST MVRETREVDE NIETVQKLLP RVVALRPKIQ KVVEEEDVEA YKSLTRVLSD
AGTAWVVAIA RETTAFRPLV DAILECAASD KDRDVIEYTF DFWYELKQLV VLERFIEARM
ELVDVYSKLV DILLKHLQYP QSEDGRDLHP RDLFDGDLVA EEKFREFRHA MGDTLKDSCE
VMGVTECLTK VLDAIKIWTQ KYASQATATS VPHWQELEAP LFSMRAMGRM VGKDENIVLP
QLMPLLVQIP AHEKLRFATI MVIGRYTEWT AAHPQFLEDQ FNYIVSSFQT DSKEVIRAAA
MAIKYFCTDC KHLLSAQVVQ LQQFYDKILD NLPDTSQEEI TEGVANVVSV QPKDDIYRLL
KLYCDPLMQR LMTKANNATD DDGKLAVADH LQLISIFVQQ VVIVPPVNAG EEDPAVKYWK
EAFPILATVL DGFIDFAPIC ERVCRCWRFM VISHRGAMTP ILPDMANKLA AGFERSRQGC
FLWVTGAILR EFSDDREHVD QGITESIYVF FEAQATNMLR FISELTPQEL PDVVEDFFRL
LIDTLLYYPQ KLIPSHLFTP ILEAGLSVLG LEQRDPLTAT LHYIRDLLSW GSKNPPSSSE
HLGPSVVEQL RQIVRQLLTA KGDVLVQRIL AGMMITFPRD CFADGSGALL TLFEIMPGEA
TVWVEQTMKL LPPGTVTPAD VQRVMVKIRE RLQSNDSGDV RQIRSILQDF TNTYRRRYIA
PRDGLGQLET ARFRFSG
//
