ID W3XGA5_PESFW Unreviewed; 388 AA.
AC W3XGA5;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN ORFNames=PFICI_03069 {ECO:0000313|EMBL:ETS85044.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS85044.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; KI912110; ETS85044.1; -; Genomic_DNA.
DR RefSeq; XP_007829841.1; XM_007831650.1.
DR AlphaFoldDB; W3XGA5; -.
DR STRING; 1229662.W3XGA5; -.
DR GeneID; 19268082; -.
DR KEGG; pfy:PFICI_03069; -.
DR eggNOG; ENOG502S31Y; Eukaryota.
DR HOGENOM; CLU_035914_2_1_1; -.
DR InParanoid; W3XGA5; -.
DR OrthoDB; 4070889at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..388
FT /note="Tyrosinase copper-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004835051"
FT DOMAIN 169..186
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 313..324
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 388 AA; 41669 MW; 11966547C35D45A4 CRC64;
MKSSLIVQLF LWGAATVSAS PVHNSIYKKP LYKRLKLVDL AQFGEGFHTI TLEEAKANAA
KNNAEHAGLL SGITGSNSKA ANTVVHNTAA STDSGNNATA VKAAAAGNCT SPATRVEWRS
LSDADKLAFV GAIKCLMNLP PSGAYSSAGS TSRYEDLVAV HSIMTDSIHM VAQFLPWHRY
YVHVFESMLR DECSYAGPMT WWNEPLDAGH FSTSPVFGAD TFGSAPLKTS DNQGTCIDDG
AFSNLTLHIG GERCLSRAVD ETATTQCSTD FVNSCNSNNK YSDMESCSEF GPHGYGHNGI
GAVMSFVSIS PGDPVFFMHH GFVDHSYVLW QNADLTNRLN QVNGCTDSAC SSQLTADYVL
SSQGLRPEVK VSDVLDTQGG YLCYVYDS
//
