ID W3XGW9_PESFW Unreviewed; 633 AA.
AC W3XGW9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=AMP-dependent synthetase/ligase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFICI_02712 {ECO:0000313|EMBL:ETS84687.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS84687.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- SIMILARITY: Belongs to the ATP-dependent AMP-binding enzyme family.
CC {ECO:0000256|ARBA:ARBA00006432}.
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DR EMBL; KI912110; ETS84687.1; -; Genomic_DNA.
DR RefSeq; XP_007829484.1; XM_007831293.1.
DR AlphaFoldDB; W3XGW9; -.
DR STRING; 1229662.W3XGW9; -.
DR GeneID; 19267725; -.
DR KEGG; pfy:PFICI_02712; -.
DR eggNOG; KOG1179; Eukaryota.
DR HOGENOM; CLU_000022_46_3_1; -.
DR InParanoid; W3XGW9; -.
DR OMA; IIHELYA; -.
DR OrthoDB; 1650656at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR PANTHER; PTHR43107:SF15; FATTY ACID TRANSPORT PROTEIN 3, ISOFORM A; 1.
DR PANTHER; PTHR43107; LONG-CHAIN FATTY ACID TRANSPORT PROTEIN; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000030651}.
FT DOMAIN 63..379
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 498..575
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 633 AA; 70497 MW; E27C6D38D36601D7 CRC64;
MALPVAGAVA GAAAIASYLD AKYHIRHDVR LGRNVGAMDR VIKFVGEKAA NEKMTVYSYF
EDRVGTPEGD YTFLIFEGKE WTYTEFFNAV QPIGNWLLKD LGVKKGEMVA LDGPNSPEWL
MLWLAVEGIG ATSAFINHNL TATSLKHSVE LGKPRFLLAD ATITNLVSPI EAGLEASGIK
TLYYSPEFLQ SFKDTENLPK ELRQKISPLA VSCLIYTSGT TGLPKGTIMD RAREIRLTSQ
SPEHVMPLKP GDRMYTCLPM FHGAGHGLCV LPCIGAGATV VLSRKFSHRT FWPEVHSSQA
NIIQYVGELC RYLVNAPPTP LDKGHNVTIA WGNGMRPDVW ETFRERFGIE CINELYAGTD
SMGFSNIQNR GDFSRSTIGV RGKLWHWWNG YREKRVLVDP DTQEILRGKD GLAIEAKAGE
AGEMIHQLDA QNPDAGSPTY FGNHGASVKR RVADVFQKGD LWFRSGDLMR LDVDGRLYFV
DRLGDTYRWK SENVSTNEVS DVVGEFPQVA ETNVYGVLVP NTDGRAGCAA VVVREGLEQL
DFAALAEHCL ARLPRYAVPV FLRVCRELEY TGTMKLQKGR LRSEGVDLDV IEKAAQDKKE
AIDSMYWLSP NGREYVPFRR KDLQQLRGGS VRL
//
