ID W3XIR3_PESFW Unreviewed; 579 AA.
AC W3XIR3;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=PFICI_03924 {ECO:0000313|EMBL:ETS85899.1};
OS Pestalotiopsis fici (strain W106-1 / CGMCC3.15140).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Sporocadaceae; Pestalotiopsis.
OX NCBI_TaxID=1229662 {ECO:0000313|EMBL:ETS85899.1, ECO:0000313|Proteomes:UP000030651};
RN [1] {ECO:0000313|Proteomes:UP000030651}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=W106-1 / CGMCC3.15140 {ECO:0000313|Proteomes:UP000030651};
RX PubMed=25623211; DOI=10.1186/s12864-014-1190-9;
RA Wang X., Zhang X., Liu L., Xiang M., Wang W., Sun X., Che Y., Guo L.,
RA Liu G., Guo L., Wang C., Yin W.B., Stadler M., Zhang X., Liu X.;
RT "Genomic and transcriptomic analysis of the endophytic fungus
RT Pestalotiopsis fici reveals its lifestyle and high potential for synthesis
RT of natural products.";
RL BMC Genomics 16:28-28(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the purine-cytosine permease (2.A.39) family.
CC {ECO:0000256|ARBA:ARBA00008974}.
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DR EMBL; KI912110; ETS85899.1; -; Genomic_DNA.
DR RefSeq; XP_007830696.1; XM_007832505.1.
DR AlphaFoldDB; W3XIR3; -.
DR GeneID; 19268937; -.
DR KEGG; pfy:PFICI_03924; -.
DR eggNOG; KOG2466; Eukaryota.
DR HOGENOM; CLU_021555_4_1_1; -.
DR InParanoid; W3XIR3; -.
DR OMA; FNWLYGF; -.
DR OrthoDB; 1218881at2759; -.
DR Proteomes; UP000030651; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd11482; SLC-NCS1sbd_NRT1-like; 1.
DR Gene3D; 1.10.4160.10; Hydantoin permease; 1.
DR InterPro; IPR012681; NCS1.
DR InterPro; IPR001248; Pur-cyt_permease.
DR InterPro; IPR045225; Uracil/uridine/allantoin_perm.
DR NCBIfam; TIGR00800; ncs1; 1.
DR PANTHER; PTHR30618; NCS1 FAMILY PURINE/PYRIMIDINE TRANSPORTER; 1.
DR PANTHER; PTHR30618:SF0; PURINE-URACIL PERMEASE NCS1; 1.
DR Pfam; PF02133; Transp_cyt_pur; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000030651};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 133..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 185..209
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 216..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 260..281
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 302..323
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 417..436
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 461..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 499..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 546..579
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 548..567
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 579 AA; 63708 MW; FB6905D7AD62E0EA CRC64;
MGMKDALQGG KAHLHAGREK LHLRLTEPSS WKLPKQHSSI APPDVWTNAD QDPVPPEKLT
WTQWTFVTYW LSDLVTISGW EAASSIVTTG LSATDAVLIT LVAGICNAIP TVLNGCIGAD
LHIPFPIAAR ASYGYWLSYF CVISRGILAL FWFGVQSAGG GDCVTAMITA IWPSYQSVPN
HLPEFVGVTT QGMVSYFIYW LIQFPLLLIP THRLQYLFNV KACLALPMAL AMVIYLSVKA
GSSSNEFFTA PATVHGSTRA WLWLSSLTSV IGGYSTLAVN IPDFSRFSRS NRDPWWQLPI
IPFFKTIVGV LGIVAASASQ QIYGTALWNP LDIVNEWQGT PGGRAAAFFC GLIWLLAQIS
VNISANAVSF ANDITTLVPK WFNVRRGTIF ASFIGGWALC PWIIMASASS FLSFMSAYAI
FMAPIAGILV TDYWLIKRRK YDVPALYDPY GIYRFGWGGN WRALVTTLLV IVPLLPALAH
KVTPNSVHIS TGLQNLFSFN WLYGFVVSIV LYYVLNVIFP HQPTLIDKVV PGYPYTIEGI
VADTESQNST REAKDEMPQK DGHGPRYSEA QEVIGSAVA
//
